March 29 – Battle of Towton: Edward IV defeats Queen Margaret, to make good his claim to the English throne (thought to be the bloodiest battle ever fought in England).
August 7 – The Ming Dynasty Chinese military general Cao Qin stages a coup against the Tianshun Emperor; after setting fire to the eastern and western gates of the Imperial City, Beijing (which are doused by pouring rains during the day-long uprising), Cao Qin finds himself hemmed in on all sides by imperial forces, loses three of his own brothers in the fight, and instead of facing execution, he flees to his home in the city, and commits suicide by jumping down a well located within his walled compound.
May 15 – Battle of Hexham: Neville defeats another Lancastrian army, this one led by King Henry and Queen Margaret themselves. This marks the end of organized Lancastrian resistance for several years.[12]
June 18 – Pope Pius II himself shoulders the cross of the Crusades, and departs for Ancona to participate in person. He names Skanderbeg general captain of the Holy See, under the title Athleta Christi. This plan forces Skanderbeg to break his ten-year peace treaty with the Ottomans signed in 1463, by attacking their forces near Ohrid.
In China, a small rebellion occurs in the interior province of Huguang, during the Ming Dynasty; a subsequent rebellion springs up in Guangxi, where a rebellion of the Miao people and Yao people forces the Ming throne to respond, by sending 30,000 troops (including 1,000 Mongol cavalry) to aid the 160,000 local troops stationed in the region, to crush the rebellion that will end in 1466.[14][15]
Jehan Lagadeuc writes a Breton-French-Latin dictionary called the Catholicon. It is the first French dictionary as well as the first Breton dictionary of world history, and it will be published in 1499.
The Great Council of the Republic of Venice attempts to curb the power of the Council of Ten through legislation restricting them to acting on emergency matters.
Marsilio Ficino completes his translation of the collected works of Plato, writes Commentary on Plato's Symposium on Love, and starts to work on Platonic Theology.