| 1921 Columbus Panhandles season | |
|---|---|
| Head coach | Ted Nesser |
| Home field | Neil Field |
| Results | |
| Record | 3–8 Overall 1–8 APFA |
| League place | 17th APFA |
The 1921 Columbus Panhandles season was their second in the newly formed American Professional Football Association (soon to become the National Football League). The team failed to improve on their previous output of 2–6–2, winning only one league game.[1] They finished seventeenth in the league.
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