Incumbent Democratic Senator Debbie Stabenow was first elected in 2000, defeating incumbent Republican Spencer Abraham. Stabenow was most recently re-elected in 2018 with 52.3% of the vote. She announced on January 5, 2023 that she would not seek a fifth term in office. This will be the first open race for this seat since 1994, which was the only time since 1972 that Republicans won a Michigan U.S. Senate race.[2][3]