AL amyloidosis

AL amyloidosis
Other namesPrimary systemic amyloidosis (PSA), primary amyloidosis
SpecialtyHematology

Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis.[1] The disease is caused when a person's antibody-producing cells do not function properly and produce abnormal protein fibers made of components of antibodies called light chains. These light chains come together to form amyloid deposits which can cause serious damage to different organs.[2][3] An abnormal light chain in urine is known as Bence Jones protein.

  1. ^ Baker KR (2022). "Light Chain Amyloidosis: Epidemiology, Staging, and Prognostication". Methodist DeBakey Cardiovascular Journal. 18 (2): 27–35. doi:10.14797/mdcvj.1070. PMC 8932379. PMID 35414848.
  2. ^ "Amyloidosis Causes, Diagnosis, Symptoms, and Treatment on MedicineNet.com".
  3. ^ "Amyloidosis and Kidney Disease". National Institute of Diabetes and Digestive and Kidney Diseases. Archived from the original on 20 November 2011. Retrieved 23 November 2011.

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