Adipogenesis

Adipogenesis is the formation of adipocytes (fat cells) from stem cells.^[1] It involves 2 phases, determination, and terminal differentiation. Determination is mesenchymal stem cells committing to the adipocyte precursor cells, also known as lipoblasts or preadipocytes which lose the potential to differentiate to other types of cells such as chondrocytes, myocytes, and osteoblasts.^[2] Terminal differentiation is that preadipocytes differentiate into mature adipocytes. Adipocytes can arise either from preadipocytes resident in adipose tissue, or from bone-marrow derived progenitor cells that migrate to adipose tissue.^[3]

^ "Adipogenesis". Merriam-Webster. Retrieved 3 January 2020.
^ Gregoire FM, Smas CM, Sul HS (July 1998). "Understanding adipocyte differentiation". Physiological Reviews. 78 (3): 783–809. doi:10.1152/physrev.1998.78.3.783. PMID 9674695. S2CID 1538359.
^ Hausman GJ, Hausman DB (2006). "Search for the preadipocyte progenitor cell". Journal of Clinical Investigation. 116 (12): 3103–3106. doi:10.1172/JCI30666. PMC 1679717. PMID 17143324.

[1] "Adipogenesis". Merriam-Webster. Retrieved 3 January 2020.

[2] Gregoire FM, Smas CM, Sul HS (July 1998). "Understanding adipocyte differentiation". Physiological Reviews. 78 (3): 783–809. doi:10.1152/physrev.1998.78.3.783. PMID 9674695. S2CID 1538359.

[pmid17143324-3] Hausman GJ, Hausman DB (2006). "Search for the preadipocyte progenitor cell". Journal of Clinical Investigation. 116 (12): 3103–3106. doi:10.1172/JCI30666. PMC 1679717. PMID 17143324.

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