Back ملزن Arabic Aglutinin Czech Agglutinine German Aglutinina Spanish Agglutinine French Aglutinina Galician Agglutinina Italian ಅಂಟಣಿಕ Kannada അഗ്ലൂട്ടിനിൻ Malayalam Agglutinin NN
An agglutinin is a substance in the blood that causes particles to coagulate and aggregate; that is, to change from fluid-like state to a thickened-mass (solid) state.[1]
Agglutinins can be antibodies that cause antigens to aggregate by binding to the antigen-binding sites of antibodies. Agglutinins can also be any substance other than antibodies, such as sugar-binding protein lectins.
When an agglutinin is added to a uniform suspension of particles, such as bacteria or blood, in a test tube (in vitro), agglutinin binds to the agglutinin-specific structure on the particle causing the particles to aggregate and fall to the bottom, leaving a clear suspension. This phenomenon known as agglutination is of great importance in medicine, as it serves as a diagnostic tool.[2]
- ^ "Agglutinin". NCI Dictionary of Cancer Terms. Retrieved 7 November 2017.
- ^ "Agglutination test definition, Types, Uses, Advantages, Disadvantages". Microbiology Note. 2020-06-29. Retrieved 2021-02-21.
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