Amine oxide

General structure of an amine oxide

In chemistry, an amine oxide, also known as an amine N-oxide or simply N-oxide, is a chemical compound that has the chemical formula R3N+−O. It contains a nitrogen-oxygen coordinate covalent bond with three additional hydrogen and/or substituent-groups attached to nitrogen. Sometimes it is written as R3N→O or, alternatively,[1] as R3N=O.

In the strict sense, the term amine oxide applies only to oxides of tertiary amines. Sometimes it is also used for the analogous derivatives of primary and secondary amines.

Examples of amine oxides include pyridine-N-oxide, a water-soluble crystalline solid with melting point 62–67 °C, and N-methylmorpholine N-oxide, which is an oxidant.

  1. ^ Durrant, Marcus C. (2015). "A quantitative definition of hypervalency". Chemical Science. 6 (11): 6614–6623. doi:10.1039/C5SC02076J. PMC 6054109. PMID 30090275.

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