Anogenital distance

Anogenital distance (AGD) is the distance from the midpoint of the anus to the genitalia, the underside of the vagina, the clitoris or the scrotum. It is considered medically significant for a number of reasons, in both humans and other animals, including sex determination and as a marker of endocrine disruptor exposure.^[1] It is regulated by dihydrotestosterone, which can be disrupted by phthalates common in plastics.

The anogenital index (AGI) is an index used to compare the AGD relative to a model based on body weight.^[2] It is computed as the AGD divided by weight [AGI = AGD/weight (mm/kg)].^[3]

^ Mammadov, E; Uncu, M; Dalkan, C (1 March 2018). "High Prenatal Exposure to Bisphenol A Reduces Anogenital Distance in Healthy Male Newborns". Journal of Clinical Research in Pediatric Endocrinology. 10 (1): 25–29. doi:10.4274/jcrpe.4817. PMC 5838369. PMID 28825590.
^ Cite error: The named reference Hood_2005 was invoked but never defined (see the help page).
^ Cite error: The named reference Swan_2005 was invoked but never defined (see the help page).

[Mammadov_et_al.,_2018-1] Mammadov, E; Uncu, M; Dalkan, C (1 March 2018). "High Prenatal Exposure to Bisphenol A Reduces Anogenital Distance in Healthy Male Newborns". Journal of Clinical Research in Pediatric Endocrinology. 10 (1): 25–29. doi:10.4274/jcrpe.4817. PMC 5838369. PMID 28825590.

[Hood_2005-2] Cite error: The named reference Hood_2005 was invoked but never defined (see the help page).

[Swan_2005-3] Cite error: The named reference Swan_2005 was invoked but never defined (see the help page).

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