Combination of | |
---|---|
Artemether | Antimalarial |
Lumefantrine | Antimalarial |
Clinical data | |
Trade names | Coartem, Riamet, Falcynate-LF |
AHFS/Drugs.com | Monograph |
MedlinePlus | a609024 |
Pregnancy category |
|
Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
CAS Number | |
ChemSpider | |
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Artemether/lumefantrine, sold under the trade name Coartem among others, is a combination of the two medications artemether and lumefantrine.[1] It is used to treat malaria caused by Plasmodium falciparum that is not treatable with chloroquine.[1] It is not typically used to prevent malaria.[1] It is taken by mouth.[1]
Common side effects include muscle and joint pains, fever, loss of appetite, and headache.[1] Serious side effects include prolongation of the QT interval.[1] While not well studied, it appears to be safe for use in pregnancy.[1] The dose does not need changing in those with mild or moderate kidney or liver problems.[1]
This combination came into medical use in 1992[2] and was developed in China.[2][3] It is on the World Health Organization's List of Essential Medicines.[4] It is not available as a generic medication.[5]
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