BAFF receptor

TNFRSF13C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1MPV, 1OQE, 1OSX, 2HFG, 3V56, 4V46
Identifiers
Aliases	TNFRSF13C, BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin, tumor necrosis factor receptor superfamily member 13C, TNF receptor superfamily member 13C
External IDs	OMIM: 606269; MGI: 1919299; HomoloGene: 49897; GeneCards: TNFRSF13C; OMA:TNFRSF13C - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	41,926,806 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	82,108,570 bp
RNA expression pattern
	Top expressed in
	spleen; ; lymph node; ; appendix; ; bone marrow cells; ; granulocyte; ; testicle; ; blood; ; tonsil; ; ventricular zone; ; mucosa of transverse colon;
	Top expressed in
	mesenteric lymph nodes; ; spleen; ; blood; ; submandibular gland; ; tunica adventitia of aorta; ; subcutaneous adipose tissue; ; tunica media of zone of aorta; ; morula; ; lumbar subsegment of spinal cord; ; granulocyte;
	More reference expression data
	n/a
Orthologs
	115650
	72049
	ENSG00000159958
	ENSMUSG00000068105
	Q96RJ3
	Q9D8D0
	NM_052945
	NM_028075; NM_001357758
	NP_443177
	NP_082351; NP_001344687
	Wikidata
View/Edit Human	View/Edit Mouse

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C) and BLyS receptor 3 (BR3), is a membrane protein of the TNF receptor superfamily which recognizes BAFF, an essential factor for B cell maturation and survival.^[5]^[6] In humans it is encoded by the TNFRSF13C gene.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000159958 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068105 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C (September 2001). "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF". Science. 293 (5537): 2108–11. Bibcode:2001Sci...293.2108T. doi:10.1126/science.1061965. PMID 11509692. S2CID 42673198.
^ Yan M, Brady JR, Chan B, Lee WP, Hsu B, Harless S, Cancro M, Grewal IS, Dixit VM (October 2001). "Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency". Current Biology. 11 (19): 1547–52. Bibcode:2001CBio...11.1547Y. doi:10.1016/S0960-9822(01)00481-X. PMID 11591325. S2CID 13925100.
^ "Entrez Gene: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000159958 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068105 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11509692-5] Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG, Hession C, Schneider P, Sizing ID, Mullen C, Strauch K, Zafari M, Benjamin CD, Tschopp J, Browning JL, Ambrose C (September 2001). "BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF". Science. 293 (5537): 2108–11. Bibcode:2001Sci...293.2108T. doi:10.1126/science.1061965. PMID 11509692. S2CID 42673198.

[6] Yan M, Brady JR, Chan B, Lee WP, Hsu B, Harless S, Cancro M, Grewal IS, Dixit VM (October 2001). "Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency". Current Biology. 11 (19): 1547–52. Bibcode:2001CBio...11.1547Y. doi:10.1016/S0960-9822(01)00481-X. PMID 11591325. S2CID 13925100.

[entrez-7] "Entrez Gene: TNFRSF13C tumor necrosis factor receptor superfamily, member 13C".

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