Protein structure found at the base of cilium or flagellum).
This article is about the basal body of eukaryotic flagellum. For structure at the base of bacterial flagellum, see Flagellum § Bacterial.
Schematic of the eukaryotic flagellum. 1-axoneme, 2-cell membrane, 3-IFT (Intraflagellar transport), 4-Basal body, 5-Cross section of flagellum, 6-Triplets of microtubules of basal body.Longitudinal section through the flagella area in Chlamydomonas reinhardtii. In the cell apex is the basal body that is the anchoring site for a flagellum. Basal bodies originate from and have a substructure similar to that of centrioles, with nine peripheral microtubule triplets (see structure at bottom center of image).
A basal body (synonymous with basal granule, kinetosome, and in older cytological literature with blepharoplast) is a protein structure found at the base of a eukaryoticundulipodium (cilium or flagellum). The basal body was named by Theodor Wilhelm Engelmann in 1880.[1][2] It is formed from a centriole and several additional protein structures, and is, essentially, a modified centriole.[3][4] The basal body serves as a nucleation site for the growth of the axoneme microtubules. Centrioles, from which basal bodies are derived, act as anchoring sites for proteins that in turn anchor microtubules, and are known as the microtubule organizing center (MTOC). These microtubules provide structure and facilitate movement of vesicles and organelles within many eukaryotic cells.
^Engelmann, T. W. (1880). Zur Anatomie und Physiologie der Flimmerzellen. Pflugers Arch. 23, 505–535.
^Bloodgood, R. A. (2009). "From Central to Rudimentary to Primary: The History of an Underappreciated Organelle Whose Time Has Come.The Primary Cilium". Primary Cilia. Methods in Cell Biology. Vol. 94. pp. 3–52. doi:10.1016/S0091-679X(08)94001-2. ISBN9780123750242. PMID20362083.