Bepridil

Bepridil
Clinical data
Trade names	Vascor
AHFS/Drugs.com	Monograph
MedlinePlus	a699051
Routes of; administration	Oral
ATC code	C08EA02 (WHO) ;
Pharmacokinetic data
Bioavailability	Well absorbed
Protein binding	99%
Metabolism	Hepatic, CYP3A4-mediated
Elimination half-life	42 hours
Excretion	Renal
Identifiers
	IUPAC name N-benzyl-N-(3-isobutoxy-2-pyrrolidin-1-yl-propyl)aniline;
CAS Number	64706-54-3 ;
PubChem CID	2351;
IUPHAR/BPS	2337;
DrugBank	DB01244 ;
ChemSpider	2261 ;
UNII	755BO701MA;
KEGG	D07520;
ChEBI	CHEBI:3061 ;
ChEMBL	ChEMBL1008 ;
CompTox Dashboard (EPA)	DTXSID3022663 ;
Chemical and physical data
Formula	C24H34N2O
Molar mass	366.549 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O(CC(C)C)CC(N1CCCC1)CN(c2ccccc2)Cc3ccccc3;
	InChI InChI=1S/C24H34N2O/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3 ; Key:UIEATEWHFDRYRU-UHFFFAOYSA-N ;
	(verify)

Bepridil (trade name Vascor) is an diamine calcium channel blocker once used to treat angina pectoris. It is no longer sold in the United States.

It is nonselective.^[1]

It has been discussed as a possible option in the treatment of atrial fibrillation.^[2]

It has been implicated in causing ventricular arrhythmia (torsades de pointes).