Bone morphogenetic protein 1

BMP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EDG, 3EDH
Identifiers
Aliases	BMP1, bone morphogenetic protein 1, OI13, PCOLC, PCP, PCP2, TLD
External IDs	OMIM: 112264; MGI: 88176; HomoloGene: 55955; GeneCards: BMP1; OMA:BMP1 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	22,212,326 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	70,520,234 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; left uterine tube; ; right adrenal cortex; ; left coronary artery; ; canal of the cervix; ; ectocervix; ; left adrenal cortex; ; right coronary artery; ; body of uterus; ; gastric mucosa;
	Top expressed in
	gastrula; ; cerebellar cortex; ; stroma of bone marrow; ; lip; ; decidua; ; body of femur; ; external carotid artery; ; internal carotid artery; ; calvaria; ; molar;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; zinc ion binding; metal ion binding; peptidase activity; protein binding; metalloendopeptidase activity; growth factor activity; hydrolase activity; metallopeptidase activity; serine-type endopeptidase activity; cytokine activity; identical protein binding;
Cellular component	Golgi apparatus; extracellular region; vesicle; extracellular space;
Biological process	skeletal system development; cell differentiation; ossification; extracellular matrix disassembly; proteolysis; multicellular organism development; cartilage development; positive regulation of cartilage development; cartilage condensation; high-density lipoprotein particle assembly; regulation of signaling receptor activity; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	649
	12153
	ENSG00000168487
	ENSMUSG00000022098
	P13497
	P98063
NM_001199; NM_006128; NM_006129; NM_006130; NM_006131;
	NM_006132
	NM_009755; NM_001360021
	NP_001190; NP_006120
	NP_033885; NP_001346950
	Wikidata
View/Edit Human	View/Edit Mouse

Bone morphogenetic protein 1, also known as BMP1, is a protein which in humans is encoded by the BMP1 gene.^[5]^[6] There are seven isoforms of the protein created by alternate splicing.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000168487 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022098 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: BMP1 bone morphogenetic protein 1".
^ Tabas JA, Zasloff M, Wasmuth JJ, Emanuel BS, Altherr MR, McPherson JD, Wozney JM, Kaplan FS (February 1991). "Bone morphogenetic protein: chromosomal localization of human genes for BMP1, BMP2A, and BMP3". Genomics. 9 (2): 283–9. doi:10.1016/0888-7543(91)90254-C. PMID 2004778.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000168487 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022098 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: BMP1 bone morphogenetic protein 1".

[pmid2004778-6] Tabas JA, Zasloff M, Wasmuth JJ, Emanuel BS, Altherr MR, McPherson JD, Wozney JM, Kaplan FS (February 1991). "Bone morphogenetic protein: chromosomal localization of human genes for BMP1, BMP2A, and BMP3". Genomics. 9 (2): 283–9. doi:10.1016/0888-7543(91)90254-C. PMID 2004778.

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