Brain metastasis

Micrograph showing a colorectal carcinoma metastasis to the cerebellum. HPS stain.

A brain metastasis is a cancer that has metastasized (spread) to the brain from another location in the body and is therefore considered a secondary brain tumor.[1][2] The metastasis typically shares a cancer cell type with the original site of the cancer.[3] Metastasis is the most common cause of brain cancer, as primary tumors that originate in the brain are less common.[4] The most common sites of primary cancer which metastasize to the brain are lung, breast, colon, kidney, and skin cancer. Brain metastases can occur months or even years after the original or primary cancer is treated. Brain metastases have a poor prognosis for cure, but modern treatments allow patients to live months and sometimes years after the diagnosis.[5]

  1. ^ Garsa A, Jang JK, Baxi S, Chen C, Akinniranye O, Hall O, Larkin J, Motala A, Hempel S (2021). "Radiation Therapy for Brain Metastases: A Systematic Review". Pract Radiat Oncol. 11 (5): 354–365. doi:10.1016/j.prro.2021.04.002. PMID 34119447. S2CID 236256085.
  2. ^ Tse V (10 November 2009). "Brain Metastasis". Medscape. Archived from the original on 16 July 2017. Retrieved 13 January 2010.
  3. ^ "Metastatic Brain Tumors" (PDF). Archived from the original (PDF) on 29 August 2017. Retrieved 13 August 2017.
  4. ^ "Tumor Types - National Brain Tumor Society". National Brain Tumor Society. Retrieved 1 August 2017.[permanent dead link]
  5. ^ "Radiation Therapy for Brain Metastases: What are brain metastases?". Archived from the original on 2010-04-06. Retrieved 2010-03-17.

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