Bromoform

Bromoform
Skeletal formula of bromoform	Stereo, skeletal formula of bromoform with the explicit hydrogen added
	; A bottle of bromoform with some in the adjacent beaker
Names
	Preferred IUPAC name Tribromomethane
	Other names Bromoform; Methenyl tribromide[citation needed]; Methyl tribromide;
Identifiers
CAS Number	75-25-2 ;
3D model (JSmol)	Interactive image;
Abbreviations	R-20B3[citation needed]; UN 2515;
Beilstein Reference	1731048
ChEBI	CHEBI:38682 ;
ChEMBL	ChEMBL345248 ;
ChemSpider	13838404 ;
DrugBank	DB03054 ;
ECHA InfoCard	100.000.777
EC Number	200-854-6;
Gmelin Reference	49500
KEGG	C14707 ;
MeSH	bromoform
PubChem CID	5558;
RTECS number	PB5600000;
UNII	TUT9J99IMU ;
UN number	2515
CompTox Dashboard (EPA)	DTXSID1021374 ;
	InChI InChI=1S/CHBr3/c2-1(3)4/h1H Key: DIKBFYAXUHHXCS-UHFFFAOYSA-N ;
	SMILES BrC(Br)Br;
Properties
Chemical formula	CHBr3
Molar mass	252.731 g·mol−1
Appearance	Colorless liquid
Density	2.89 g/cm3
Melting point	8.69 °C; 47.64 °F; 281.84 K
Boiling point	149.40 °C; 300.92 °F; 422.55 K
Solubility in water	3.2 g L−1 (at 30 °C)
log P	2.435
Vapor pressure	670 Pa (at 20.0 °C)
Henry's law; constant (kH)	17 μmol Pa−1 kg−1
Acidity (pKa)	13.7
Magnetic susceptibility (χ)	-82.60·10−6 cm3/mol
Refractive index (nD)	1.595
Thermochemistry
Heat capacity (C)	130.5 J K−1 mol−1
Std enthalpy of; formation (ΔfH⦵298)	6.1–12.7 kJ mol−1
Std enthalpy of; combustion (ΔcH⦵298)	−549.1–−542.5 kJ mol−1
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H302, H315, H319, H331, H411
Precautionary statements	P261, P273, P305+P351+P338, P311
NFPA 704 (fire diamond)	3 0 0
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	933.0 mg kg−1 (oral, rat)
LDLo (lowest published)	1400 mg/kg (mouse, oral); 1147 mg/kg (rat, oral)
LC50 (median concentration)	1151 ppm (mammal)
LCLo (lowest published)	4282 ppm (rat, 4 hr); 7000 ppm (dog, 1 hr)
	NIOSH (US health exposure limits):
PEL (Permissible)	TWA 0.5 ppm (5 mg/m3) [skin]
REL (Recommended)	TWA 0.5 ppm (5 mg/m3) [skin]
IDLH (Immediate danger)	850 ppm
Related compounds
Related alkanes	Dibromomethane; Tetrabromomethane; 1,1-Dibromoethane; 1,2-Dibromoethane; Tetrabromoethane;
Supplementary data page
	Bromoform (data page)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Bromoform is an organic compound with the chemical formula CHBr₃. It is a colorless liquid at room temperature, with a high refractive index and a very high density. Its sweet odor is similar to that of chloroform. It is one of the four haloforms, the others being fluoroform, chloroform, and iodoform. It is a brominated organic solvent. Currently its main use is as a laboratory reagent. It is very slightly soluble in water (one part bromoform in 800 parts water) and is miscible with alcohol, benzene, chloroform, ether, petroleum ether, acetone and oils.

^ ^a ^b Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 661. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The retained names 'bromoform' for HCBr₃, 'chloroform' for HCCl₃, and 'iodoform' for HCI₃ are acceptable in general nomenclature. Preferred IUPAC names are substitutive names.
^ ^a ^b ^c ^d NIOSH Pocket Guide to Chemical Hazards. "#0066". National Institute for Occupational Safety and Health (NIOSH).
^ Rumble, John (18 June 2018). CRC Handbook of Chemistry and Physics. CRC Press. pp. 3–50. ISBN 9781138561632.
^ ^a ^b ^c "Bromoform". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).

[iupac2013-1] Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 661. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. The retained names 'bromoform' for HCBr₃, 'chloroform' for HCCl₃, and 'iodoform' for HCI₃ are acceptable in general nomenclature. Preferred IUPAC names are substitutive names.

[PGCH-2] NIOSH Pocket Guide to Chemical Hazards. "#0066". National Institute for Occupational Safety and Health (NIOSH).

[3] Rumble, John (18 June 2018). CRC Handbook of Chemistry and Physics. CRC Press. pp. 3–50. ISBN 9781138561632.

[IDLH-4] "Bromoform". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).

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