CCR3 (gene)

CCR3
Identifiers
Aliases	CCR3, CC-CKR-3, CD193, CKR3, CMKBR3, C-C motif chemokine receptor 3, CKR 3, C C CKR3
External IDs	OMIM: 601268; MGI: 104616; HomoloGene: 20436; GeneCards: CCR3; OMA:CCR3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	46,266,706 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	123,831,726 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; blood; ; muscle of thigh; ; monocyte; ; gallbladder; ; appendix; ; gonad; ; muscle of arm; ; biceps brachii; ; granulocyte;
	Top expressed in
	embryo; ; spleen; ; granulocyte; ; zygote; ; intestinal villus; ; bone marrow; ; Ileal epithelium; ; secondary oocyte; ; blood; ; cervix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding; C-C chemokine receptor activity; chemokine receptor activity; C-C chemokine binding; chemokine binding;
Cellular component	integral component of membrane; membrane; integral component of plasma membrane; plasma membrane; cytoplasm; external side of plasma membrane;
Biological process	positive regulation of endothelial cell proliferation; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration; chemokine-mediated signaling pathway; positive regulation of angiogenesis; chemotaxis; cellular defense response; cell adhesion; inflammatory response; viral process; signal transduction; G protein-coupled receptor signaling pathway; immune response; calcium-mediated signaling; cell chemotaxis;
	Sources:Amigo / QuickGO
Orthologs
	1232
	12771
	ENSG00000183625
	ENSMUSG00000035448
	P51677
	P51678
	NM_001164680; NM_001837; NM_178328; NM_178329
	NM_009914
	NP_001158152; NP_001828; NP_847898; NP_847899
	NP_034044
	Wikidata
View/Edit Human	View/Edit Mouse

C-C chemokine receptor type 3 is a protein that in humans is encoded by the CCR3 gene.^[5]

CCR3 has also recently been designated CD193 (cluster of differentiation 193).

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183625 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000035448 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: CCR3 chemokine (C-C motif) receptor 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000183625 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000035448 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: CCR3 chemokine (C-C motif) receptor 3".

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