CD30

TNFRSF8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1D01
Identifiers
Aliases	TNFRSF8, CD30, D1S166E, Ki-1, tumor necrosis factor receptor superfamily member 8, TNF receptor superfamily member 8
External IDs	OMIM: 153243; MGI: 99908; HomoloGene: 949; GeneCards: TNFRSF8; OMA:TNFRSF8 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	12,144,207 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	145,041,734 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; testicle; ; blood; ; pancreatic ductal cell; ; decidua; ; subcutaneous adipose tissue; ; periodontal fiber; ; appendix; ; right auricle;
	Top expressed in
	neural layer of retina; ; blastocyst; ; secondary oocyte; ; embryo; ; zygote; ; morula; ; embryo; ; thymus; ; dentate gyrus of hippocampal formation granule cell; ; primary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane signaling receptor activity; tumor necrosis factor-activated receptor activity; nerve growth factor binding;
Cellular component	cytoplasm; integral component of membrane; integral component of plasma membrane; extracellular exosome; membrane; plasma membrane; nucleus; neuron projection;
Biological process	apoptotic signaling pathway; cellular response to mechanical stimulus; response to lipopolysaccharide; inflammatory response; immune response; signal transduction; negative regulation of cell population proliferation; positive regulation of apoptotic process; tumor necrosis factor-mediated signaling pathway; axon guidance; negative regulation of neuron projection development; positive regulation of NF-kappaB transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
	943
	21941
	ENSG00000120949
	ENSMUSG00000028602
	P28908
	Q60846
	NM_001243; NM_001281430; NM_152942
	NM_009401
	NP_001234; NP_001268359
	NP_033427
	Wikidata
View/Edit Human	View/Edit Mouse

CD30, also known as TNFRSF8 (TNF receptor superfamily member 8),^[5] is a cell membrane protein of the tumor necrosis factor receptor family and a tumor marker.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120949 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028602 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: TNFRSF8 tumor necrosis factor receptor superfamily member 8". National Library of Medicine, National Center for Biotechnology Information. 22 September 2022. Retrieved 6 November 2022.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000120949 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028602 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: TNFRSF8 tumor necrosis factor receptor superfamily member 8". National Library of Medicine, National Center for Biotechnology Information. 22 September 2022. Retrieved 6 November 2022.

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