CD300C

CD300C
Identifiers
Aliases	CD300C, CLM-6, CMRF-35, CMRF-35A, CMRF35, CMRF35-A1, CMRF35A, CMRF35A1, IGSF16, LIR, CD300c molecule
External IDs	OMIM: 606786; MGI: 2153249; HomoloGene: 74580; GeneCards: CD300C; OMA:CD300C - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	74,546,115 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	114,892,706 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; blood; ; spleen; ; upper lobe of left lung; ; appendix; ; right lung; ; bone marrow; ; right coronary artery; ; Descending thoracic aorta;
	Top expressed in
	stroma of bone marrow; ; granulocyte; ; spleen; ; blood; ; calvaria; ; right lung lobe; ; mesenteric lymph nodes; ; tibiofemoral joint; ; thymus; ; seminal vesicula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transmembrane signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	cellular defense response; immune system process; regulation of immune response; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	10871
	140497
	ENSG00000167850
	ENSMUSG00000044811
	Q08708
	Q7TSN2
	NM_006678
	NM_134158
	NP_006669
	NP_598919
	Wikidata
View/Edit Human	View/Edit Mouse

CMRF35-like molecule 6 (CLM-6) also known as CD300 antigen-like family member C (CD300c) is a protein that in humans is encoded by the CD300C gene.^[5]^[6]^[7]

The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167850 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044811 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Jackson DG, Hart DN, Starling G, Bell JI (Jun 1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor". Eur J Immunol. 22 (5): 1157–63. doi:10.1002/eji.1830220508. PMID 1349532. S2CID 23437463.
^ Clark GJ, Green BJ, Hart DN (Aug 2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17". Tissue Antigens. 55 (2): 101–9. doi:10.1034/j.1399-0039.2000.550201.x. PMID 10746781.
^ ^a ^b "Entrez Gene: CD300C CD300c molecule".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000167850 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000044811 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1349532-5] Jackson DG, Hart DN, Starling G, Bell JI (Jun 1992). "Molecular cloning of a novel member of the immunoglobulin gene superfamily homologous to the polymeric immunoglobulin receptor". Eur J Immunol. 22 (5): 1157–63. doi:10.1002/eji.1830220508. PMID 1349532. S2CID 23437463.

[pmid10746781-6] Clark GJ, Green BJ, Hart DN (Aug 2000). "The CMRF-35H gene structure predicts for an independently expressed member of an ITIM/ITAM pair of molecules localized to human chromosome 17". Tissue Antigens. 55 (2): 101–9. doi:10.1034/j.1399-0039.2000.550201.x. PMID 10746781.

[entrez-7] "Entrez Gene: CD300C CD300c molecule".

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