CD63

CD63
Identifiers
Aliases	CD63, LAMP-3, ME491, MLA1, OMA81H, TSPAN30, CD63 molecule
External IDs	OMIM: 155740; MGI: 99529; HomoloGene: 37526; GeneCards: CD63; OMA:CD63 - orthologs
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.2 Start 55,725,323 bp[1] End 55,729,707 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10 D3|10 77.19 cM Start 128,736,858 bp[2] End 128,748,691 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium tendon of biceps brachii beta cell lower lobe of lung upper lobe of lung left adrenal gland olfactory bulb Descending thoracic aorta upper lobe of left lung decidua Top expressed in right kidney proximal tubule human kidney islet of Langerhans morula blastocyst yolk sac stomach urinary bladder adrenal gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component integral component of membrane multivesicular body endosome multivesicular body membrane membrane late endosome membrane intrinsic component of plasma membrane melanosome plasma membrane integral component of plasma membrane endosome lumen multivesicular body, internal vesicle lysosomal membrane extracellular region platelet dense granule membrane lysosome endosome membrane extracellular exosome extracellular space cell surface azurophil granule membrane late endosome Biological process positive regulation of receptor internalization platelet degranulation pigment granule maturation endosome to melanosome transport protein transport positive regulation of integrin-mediated signaling pathway cell-matrix adhesion cell migration neutrophil degranulation transport pigmentation pigment cell differentiation regulation of vascular endothelial growth factor signaling pathway cell surface receptor signaling pathway positive regulation of endocytosis regulation of potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 967 12512 Ensembl ENSG00000135404 ENSMUSG00000025351 UniProt P08962 P41731 RefSeq (mRNA) NM_001780 NM_001040034 NM_001257389 NM_001257390 NM_001257391 NM_001257392 NM_001257400 NM_001257401 NM_001267698 NM_001042580 NM_001282966 NM_007653 RefSeq (protein) NP_001244318 NP_001244319 NP_001244320 NP_001244321 NP_001244329 NP_001244330 NP_001254627 NP_001771 NP_001036045 NP_001269895 NP_031679 Location (UCSC) Chr 12: 55.73 – 55.73 Mb Chr 10: 128.74 – 128.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

CD63 antigen is a protein that, in humans, is encoded by the CD63 gene.^[5] CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced.