CD93

CD93
Identifiers
Aliases	CD93, C1QR1, C1qR(P), C1qRP, CDw93, ECSM3, MXRA4, dJ737E23.1, CD93 molecule
External IDs	OMIM: 120577; MGI: 106664; HomoloGene: 7823; GeneCards: CD93; OMA:CD93 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	23,086,324 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	148,285,483 bp
RNA expression pattern
	Top expressed in
	visceral pleura; ; lower lobe of lung; ; parietal pleura; ; monocyte; ; periodontal fiber; ; placenta; ; pericardium; ; vena cava; ; trabecular bone; ; superficial temporal artery;
	Top expressed in
	left lung; ; left lung lobe; ; right lung; ; right lung lobe; ; stroma of bone marrow; ; atrioventricular valve; ; external carotid artery; ; atrium; ; internal carotid artery; ; body of femur;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; complement component C1q complex binding; protein binding; carbohydrate binding; signaling receptor activity;
Cellular component	cell surface; membrane; plasma membrane; secretory granule membrane; cytoplasmic vesicle; specific granule membrane; tertiary granule membrane; ficolin-1-rich granule membrane; integral component of membrane;
Biological process	phagocytosis; macrophage activation; cell adhesion; viral process; neutrophil degranulation; cell-cell adhesion; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	22918
	17064
	ENSG00000125810
	ENSMUSG00000027435
	Q9NPY3
	O89103
	NM_012072
	NM_010740
	NP_036204
	NP_034870
	Wikidata
View/Edit Human	View/Edit Mouse

CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene.^[5]^[6]^[7] CD93 is a C-type lectin transmembrane receptor which plays a role not only in cell–cell adhesion processes but also in host defense.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000125810 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000027435 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nepomuceno RR, Henschen-Edman AH, Burgess WH, Tenner AJ (February 1997). "cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro". Immunity. 6 (2): 119–29. doi:10.1016/S1074-7613(00)80419-7. PMID 9047234.
^ Webster SD, Park M, Fonseca MI, Tenner AJ (January 2000). "Structural and functional evidence for microglial expression of C1qR(P), the C1q receptor that enhances phagocytosis". Journal of Leukocyte Biology. 67 (1): 109–16. doi:10.1002/jlb.67.1.109. PMID 10648005. S2CID 14982216.
^ ^a ^b "Entrez Gene: CD93 CD93 molecule".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000125810 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000027435 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9047234-5] Nepomuceno RR, Henschen-Edman AH, Burgess WH, Tenner AJ (February 1997). "cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro". Immunity. 6 (2): 119–29. doi:10.1016/S1074-7613(00)80419-7. PMID 9047234.

[pmid10648005-6] Webster SD, Park M, Fonseca MI, Tenner AJ (January 2000). "Structural and functional evidence for microglial expression of C1qR(P), the C1q receptor that enhances phagocytosis". Journal of Leukocyte Biology. 67 (1): 109–16. doi:10.1002/jlb.67.1.109. PMID 10648005. S2CID 14982216.

[entrez-7] "Entrez Gene: CD93 CD93 molecule".

[1]

[2]

[3]

[4]

[5]

[6]

[7]