DDR1

DDR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3ZOS, 4AG4, 4BKJ, 4CKR, 5BVK, 5BVN, 5BVO, 5BVW, 5FDP
Identifiers
Aliases	DDR1, CAK, CD167, DDR, EHGK2, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE, discoidin domain receptor tyrosine kinase 1
External IDs	OMIM: 600408; MGI: 99216; HomoloGene: 68212; GeneCards: DDR1; OMA:DDR1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	30,900,156 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	36,015,513 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; right uterine tube; ; ganglionic eminence; ; olfactory zone of nasal mucosa; ; C1 segment; ; minor salivary glands; ; islet of Langerhans; ; skin of abdomen; ; mucosa of esophagus; ; substantia nigra;
	Top expressed in
	ciliary body; ; iris; ; Epithelium of choroid plexus; ; retinal pigment epithelium; ; conjunctival fornix; ; Rostral migratory stream; ; medial ganglionic eminence; ; epithelium of stomach; ; motor neuron; ; parotid gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; collagen binding; metal ion binding; kinase activity; protein binding; transmembrane receptor protein tyrosine kinase activity; protein tyrosine kinase collagen receptor activity; protein tyrosine kinase activity; ATP binding; receptor tyrosine kinase;
Cellular component	integral component of membrane; membrane; receptor complex; plasma membrane; integral component of plasma membrane; extracellular region; extracellular exosome; extracellular space;
Biological process	collagen-activated tyrosine kinase receptor signaling pathway; branching involved in mammary gland duct morphogenesis; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway; female pregnancy; extracellular matrix organization; ear development; mammary gland alveolus development; regulation of extracellular matrix disassembly; smooth muscle cell migration; smooth muscle cell-matrix adhesion; regulation of cell-matrix adhesion; protein phosphorylation; cell adhesion; regulation of cell growth; peptidyl-tyrosine phosphorylation; lactation; wound healing, spreading of cells; embryo implantation; negative regulation of cell population proliferation; peptidyl-tyrosine autophosphorylation; protein autophosphorylation; axon development; neuron projection extension; cell-matrix adhesion; positive regulation of cell population proliferation; cell differentiation; regulation of extracellular matrix organization;
	Sources:Amigo / QuickGO
Orthologs
	780
	12305
ENSG00000215522; ENSG00000137332; ENSG00000229767; ENSG00000230456; ENSG00000234078;
	ENSG00000204580; ENSG00000223680
	ENSMUSG00000003534
	Q08345
	Q03146
NM_001202521; NM_001202522; NM_001202523; NM_001297652; NM_001297653;
	NM_001297654; NM_001954; NM_013993; NM_013994
	NM_001198831; NM_001198833; NM_007584; NM_172962
NP_001189450; NP_001189451; NP_001189452; NP_001284581; NP_001284582;
	NP_001284583; NP_001945; NP_054699; NP_054700; NP_001284583.1; NP_054699.2
	NP_001185760; NP_001185762; NP_031610; NP_766550
	Wikidata
View/Edit Human	View/Edit Mouse

Discoidin domain receptor family, member 1, also known as DDR1 or CD167a (cluster of differentiation 167a), is a human gene.^[5]

^ ^a ^b ^c ENSG00000137332, ENSG00000229767, ENSG00000230456, ENSG00000234078, ENSG00000204580, ENSG00000223680 GRCh38: Ensembl release 89: ENSG00000215522, ENSG00000137332, ENSG00000229767, ENSG00000230456, ENSG00000234078, ENSG00000204580, ENSG00000223680 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003534 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: DDR1 discoidin domain receptor family, member 1".

[refGRCh38Ensembl-1] ENSG00000137332, ENSG00000229767, ENSG00000230456, ENSG00000234078, ENSG00000204580, ENSG00000223680 GRCh38: Ensembl release 89: ENSG00000215522, ENSG00000137332, ENSG00000229767, ENSG00000230456, ENSG00000234078, ENSG00000204580, ENSG00000223680 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003534 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: DDR1 discoidin domain receptor family, member 1".

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