Back فيروس الضنك Arabic فيروس الدينجى ARZ डेंगू वायरस Bihari ডেঙ্গু ভাইরাস Bengali/Bangla Denguevirus Danish Dengue-Virus German Virus dengue Spanish ویروس تب دنگی Persian Virus de la dengue French Dengue-wiirus FRR
| Dengue virus | |
|---|---|
| |
| A TEM micrograph showing dengue virus virions (the cluster of dark dots near the center) | |
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Kitrinoviricota |
| Class: | Flasuviricetes |
| Order: | Amarillovirales |
| Family: | Flaviviridae |
| Genus: | Flavivirus |
| Species: | Dengue virus
|
Dengue virus (DENV) is the cause of dengue fever. It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus.[1][2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed,[3][4][5] all of which can cause the full spectrum of disease.[1] Nevertheless, scientists' understanding of dengue virus may be simplistic as, rather than distinct antigenic groups, a continuum appears to exist.[6] This same study identified 47 strains of dengue virus.[7] Additionally, coinfection with and lack of rapid tests for Zika virus and chikungunya complicate matters in real-world infections.[8]
Dengue virus has increased dramatically within the last 20 years, becoming one of the worst mosquito-borne human pathogens that tropical countries have to deal with. 2013 estimates indicate that as many as 390 million infections occur each year, and many dengue infections are increasingly understood to be asymptomatic or subclinical.[9]
- ^ a b Rodenhuis-Zybert IA, Wilschut J, Smit JM (August 2010). "Dengue virus life cycle: viral and host factors modulating infectivity". Cellular and Molecular Life Sciences. 67 (16): 2773–86. doi:10.1007/s00018-010-0357-z. PMC 11115823. PMID 20372965. S2CID 4232236.
- ^ WHO (2009). Dengue Guidelines for Diagnosis, Treatment, Prevention and Control (PDF). World Health Organization. ISBN 978-92-4-154787-1.
- ^ Normile D (October 2013). "Tropical medicine. Surprising new dengue virus throws a spanner in disease control efforts". Science. 342 (6157): 415. Bibcode:2013Sci...342..415N. doi:10.1126/science.342.6157.415. PMID 24159024.
- ^ Dwivedi, V. D., Tripathi, I. P., Tripathi, R. C., Bharadwaj, S., & Mishra, S. K. (2017). Genomics, proteomics and evolution of Dengue virus. Briefings in functional genomics.16(4): 217–227, https://doi.org/10.1093/bfgp/elw040
- ^ Taylor-Robinson, Andrew W. (2016-03-03). "A Putative Fifth Serotype of Dengue - Potential Implications for Diagnosis, Therapy and Vaccine Design". International Journal of Clinical & Medical Microbiology. 2016. doi:10.15344/2456-4028/2016/101. ISSN 2456-4028.
- ^ "A new understanding of Dengue virus". ScienceDaily. September 18, 2015. Retrieved May 7, 2016.
- ^ "A Second Time Dengue Infection Can be Life-Threatening Says Research". NDTV. United Kingdom. September 18, 2015. Retrieved 2016-05-07.
- ^ Vogels CB, Rückert C, Cavany SM, Perkins TA, Ebel GD, Grubaugh ND (January 2019). "Arbovirus coinfection and co-transmission: A neglected public health concern?". PLOS Biology. 17 (1): e3000130. doi:10.1371/journal.pbio.3000130. PMC 6358106. PMID 30668574.
- ^ Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, Drake JM, Brownstein JS, Hoen AG, Sankoh O, Myers MF, George DB, Jaenisch T, Wint GR, Simmons CP, Scott TW, Farrar JJ, Hay SI (April 2013). "The global distribution and burden of dengue". Nature. 496 (7446): 504–7. Bibcode:2013Natur.496..504B. doi:10.1038/nature12060. PMC 3651993. PMID 23563266.
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