Dexrazoxane

Dexrazoxane

Clinical data
AHFS/Drugs.com	Monograph
MedlinePlus	a609010
License data	US DailyMed: Dexrazoxane
Routes of administration	Intravenous
ATC code	V03AF02 (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
IUPAC name 4-[(2S)-2-(3,5-Dioxopiperazin-1-yl)propyl]piperazine-2,6-dione
CAS Number	24584-09-6 Y
PubChem CID	71384
IUPHAR/BPS	7330
DrugBank	DB00380 Y
ChemSpider	64479 Y
UNII	048L81261F
KEGG	D03730 Y as HCl: D07807 Y
ChEBI	CHEBI:50223 Y
ChEMBL	ChEMBL1738 Y
CompTox Dashboard (EPA)	DTXSID3040647
ECHA InfoCard	100.163.459
Chemical and physical data
Formula	C11H16N4O4
Molar mass	268.273 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2NC(=O)CN(C[C@@H](N1CC(=O)NC(=O)C1)C)C2
InChI InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1 Y Key:BMKDZUISNHGIBY-ZETCQYMHSA-N Y
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Dexrazoxane hydrochloride (Zinecard, Cardioxane) is a cardioprotective agent. It was discovered by Eugene Herman in 1972. The IV administration of dexrazoxane is in acidic condition with HCl adjusting the pH.^[1]