Dysthymia

Dysthymia
Other namesPersistent depressive disorder, dysthymic disorder, chronic depression[1]
SpecialtyPsychiatry, clinical psychology
SymptomsLow mood, low self-esteem, loss of interest in normally enjoyable activities, low energy, pain without a clear cause[2]
ComplicationsSelf-harm, suicide
Usual onsetEarly adulthood
CausesGenetic, environmental, and psychological factors[2]
Risk factorsFamily history, major life changes, certain medications, chronic health problems, substance use disorders[2][3]
TreatmentCounseling, antidepressant medication, electroconvulsive therapy[2]
Frequency104 million (2015)[4]

Dysthymia (/dɪsˈθmiə/ dihs-THIY-mee-uh), known as persistent depressive disorder (PDD) in the DSM-5-TR[5] and dysthymic disorder in ICD-11,[6] is a psychiatric condition marked by symptoms that are similar to those of major depressive disorder, but which persist for at least two years in adults and one year among pediatric populations.[7][8] The term was introduced by Robert Spitzer in the late 1970s as a replacement for the concept of "depressive personality."[9]

With the DSM-5's publication in 2013, the condition assumed its current name (i.e., PDD), having been called dysthymic disorder in the DSM's previous edition (DSM-IV), and remaining so in ICD-11. PDD is defined by a 2-year history of symptoms of major depression not better explained by another health condition, as well as significant distress or functional impairment.[8]

Individuals with PDD, defined in part by its chronicity, may experience symptoms for years before receiving a diagnosis, if one is received at all. Consequently, they might perceive their dysphoria as a character or personality trait rather than a distinct medical condition and never discuss their symptoms with healthcare providers.[10][11] PDD subsumed prior DSM editions' diagnoses of chronic major depressive disorder and dysthymic disorder.[3] The change arose from a continuing lack of evidence of a clinically meaningful distinction between chronic major depression and dysthymic disorder.[8]

  1. ^ MedlinePlus Encyclopedia: Persistent depressive disorder
  2. ^ a b c d "Depression". NIMH. May 2016. Archived from the original on 5 August 2016. Retrieved 31 July 2016.
  3. ^ a b American Psychiatric Association (2013). Diagnostic and Statistical Manual of Mental Disorder, Fifth Edition. Washington, DC: American Psychiatric Publishing. pp. 168–171. ISBN 978-0-89042-554-1.
  4. ^ GBD 2015 Disease and Injury Incidence and Prevalence Collaborators (8 October 2016). "Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577. PMID 27733282.
  5. ^ "Depressive disorders". Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision. Washington, DC: American Psychiatric Association. 2022. ISBN 978-0-89042-576-3.
  6. ^ Clinical Descriptions and Diagnostic Requirements for ICD-11 Mental, Behavioural and Neurodevelopmental Disorders. Geneva: World Health Organization. 2024. pp. 255–258. ISBN 978-92-4-007726-3.
  7. ^ Patel, Raj K.; Aslam, Sunny P.; Rose, Gregory M. (2025), "Persistent Depressive Disorder", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 31082096, retrieved 24 March 2025
  8. ^ a b c Schramm, Elisabeth; Klein, Daniel N; Elsaesser, Moritz; Furukawa, Toshi A; Domschke, Katharina (1 September 2020). "Review of dysthymia and persistent depressive disorder: history, correlates, and clinical implications". The Lancet Psychiatry. 7 (9): 801–812. doi:10.1016/S2215-0366(20)30099-7.
  9. ^ Brody, Jane (18 January 1995). "Dysthymia: help for chronic sadness". The New York Times. New York City. p. C8. Retrieved 24 March 2025.{{cite news}}: CS1 maint: url-status (link)
  10. ^ Akiskal, H. S. (January 1983). "Dysthymic disorder: psychopathology of proposed chronic depressive subtypes". The American Journal of Psychiatry. 140 (1): 11–20. doi:10.1176/ajp.140.1.11. ISSN 0002-953X. PMID 6336637.
  11. ^ Klein, D. N.; Riso, L. P.; Anderson, R. L. (1993). "DSM-III-R dysthymia: antecedents and underlying assumptions". Progress in Experimental Personality & Psychopathology Research. 16: 222–253. ISSN 1056-7151. PMID 8293082.

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