E. Donnall Thomas

E. Donnall Thomas
Thomas in 2000
Born
Edward Donnall Thomas

(1920-03-15)March 15, 1920
DiedOctober 20, 2012(2012-10-20) (aged 92)
Alma materUniversity of Texas at Austin (BA, MA)
Harvard University (MD)
Known forTransplantation
AwardsNobel Prize in Physiology or Medicine
National Medal of Science
Scientific career
FieldsMedicine
InstitutionsMary Imogene Bassett Hospital
Notable studentsEloise Giblett

Edward Donnall "Don" Thomas (March 15, 1920 – October 20, 2012)[1] was an American physician, professor emeritus at the University of Washington, and director emeritus of the clinical research division at the Fred Hutchinson Cancer Research Center. In 1990 he shared the Nobel Prize in Physiology or Medicine with Joseph E. Murray for the development of cell and organ transplantation. Thomas and his wife and research partner Dottie Thomas developed bone marrow transplantation as a treatment for leukemia.

Thomas was a lead investigator in a failed series of experimental treatments for leukemia and for Graft-versus-host disease at Seattle's Fred Hutchinson Cancer Research Center from 1981 to 1993. Participants were not informed that Thomas and other researchers had a potential financial conflict of interest in the trials, and were never properly informed of the risks. The study continued despite objections from members of the Center’s Internal Review Board. 84 of the 85 participants in the study died.[2]

  1. ^ Frederick R. Appelbaum. Perspective: E. Donnall Thomas (1920–2012) Science 338(6111):1163, 30 November 2012
  2. ^ Seattle, Times (2001). "He saw the tests as a violation of 'trusting, desperate human beings'". Seattle Times. Seattle Times. Retrieved May 27, 2024.

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