Elongation factor

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Elongation factors are a set of proteins that function at the ribosome, during protein synthesis, to facilitate translational elongation from the formation of the first to the last peptide bond of a growing polypeptide. Most common elongation factors in prokaryotes are EF-Tu, EF-Ts, EF-G.^[1] Bacteria and eukaryotes use elongation factors that are largely homologous to each other, but with distinct structures and different research nomenclatures.^[2]

Elongation is the most rapid step in translation.^[3] In bacteria, it proceeds at a rate of 15 to 20 amino acids added per second (about 45-60 nucleotides per second).^{[citation needed]} In eukaryotes the rate is about two amino acids per second (about 6 nucleotides read per second).^{[citation needed]} Elongation factors play a role in orchestrating the events of this process, and in ensuring the high accuracy translation at these speeds.^{[citation needed]}