Enterotoxin

Staph/Strep enterotoxin, C terminal
identification of a secondary zinc-binding site in staphylococcal enterotoxin c2: implications for superantigen recognition
Identifiers
SymbolStap_Strp_tox_C
PfamPF02876
Pfam clanCL0386
InterProIPR006123
PROSITEPDOC00250
SCOP21se3 / SCOPe / SUPFAM
OPM superfamily364
OPM protein1dyq
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

An enterotoxin is a protein exotoxin released by a microorganism that targets the intestines.[1] They can be chromosomally or plasmid encoded.[2] They are heat labile (>60⁰), of low molecular weight and water-soluble. Enterotoxins are frequently cytotoxic and kill cells by altering the apical membrane permeability of the mucosal (epithelial) cells of the intestinal wall. They are mostly pore-forming toxins (mostly chloride pores), secreted by bacteria, that assemble to form pores in cell membranes. This causes the cells to die.

  1. ^ "enterotoxin" at Dorland's Medical Dictionary
  2. ^ Carlton Gyles, Magdalene So, Stanley Falkow, Journal of Infectious Diseases (1974) 130 (1): 40-49.

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