Fatty acid degradation

Fatty acid degradation is the process in which fatty acids are broken down into their metabolites, in the end generating acetyl-CoA, the entry molecule for the citric acid cycle, the main energy supply of living organisms, including bacteria and animals.[1][2] It includes three major steps:

  • Lipolysis of and release from adipose tissue
  • Activation and transport into mitochondria
  • β-oxidation
  1. ^ Fujita, Yasutaro; Matsuoka, Hiroshi; Hirooka, Kazutake (November 2007). "Regulation of fatty acid metabolism in bacteria". Molecular Microbiology. 66 (4): 829–839. doi:10.1111/j.1365-2958.2007.05947.x. ISSN 0950-382X. PMID 17919287. S2CID 43691631.
  2. ^ Novak, John T.; Carlson, Dale A. (1970). "The Kinetics of Anaerobic Long Chain Fatty Acid Degradation". Journal (Water Pollution Control Federation). 42 (11): 1932–1943. ISSN 0043-1303. JSTOR 25036816.

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