Gene product

A gene product is the biochemical material, either RNA or protein, resulting from the expression of a gene. A measurement of the amount of gene product is sometimes used to infer how active a gene is. Abnormal amounts of gene product can be correlated with disease-causing alleles, such as the overactivity of oncogenes, which can cause cancer.^[1]^[2] A gene is defined as "a hereditary unit of DNA that is required to produce a functional product".^[3] Regulatory elements include:

These elements work in combination with the open reading frame to create a functional product. This product may be transcribed and be functional as RNA or is translated from mRNA to a protein to be functional in the cell.

^ Fearon ER, Vogelstein B (June 1990). "A genetic model for colorectal tumorigenesis". Cell. 61 (5): 759–67. doi:10.1016/0092-8674(90)90186-I. PMID 2188735. S2CID 22975880.
^ Croce CM (January 2008). "Oncogenes and cancer". The New England Journal of Medicine. 358 (5): 502–11. doi:10.1056/NEJMra072367. PMID 18234754.
^ Nussbaum, Robert L.; McInnes, Roderick R.; Willard, Huntington (2016). Thompson & Thompson Genetics in Medicine (8 ed.). Philadelphia: Elsevier.

[1] Fearon ER, Vogelstein B (June 1990). "A genetic model for colorectal tumorigenesis". Cell. 61 (5): 759–67. doi:10.1016/0092-8674(90)90186-I. PMID 2188735. S2CID 22975880.

[2] Croce CM (January 2008). "Oncogenes and cancer". The New England Journal of Medicine. 358 (5): 502–11. doi:10.1056/NEJMra072367. PMID 18234754.

[3] Nussbaum, Robert L.; McInnes, Roderick R.; Willard, Huntington (2016). Thompson & Thompson Genetics in Medicine (8 ed.). Philadelphia: Elsevier.

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