Genetic screen

A genetic screen or mutagenesis screen is an experimental technique used to identify and select individuals who possess a phenotype of interest in a mutagenized population.^[1] Hence a genetic screen is a type of phenotypic screen. Genetic screens can provide important information on gene function as well as the molecular events that underlie a biological process or pathway. While genome projects have identified an extensive inventory of genes in many different organisms, genetic screens can provide valuable insight as to how those genes function.^[2]^[3]^[4]^[5]^[6]

^ Hartwell LH, Hood L, Goldberg ML, Reynolds AE, Silver LM, Veres RC (2008). Genetics: from genes to genomes. Boston: McGraw-Hill Higher Education. ISBN 978-0-07-284846-5.
^ Patton EE, Zon LI (December 2001). "The art and design of genetic screens: zebrafish". Nature Reviews. Genetics. 2 (12): 956–966. doi:10.1038/35103567. PMID 11733748. S2CID 3166016.
^ Page DR, Grossniklaus U (February 2002). "The art and design of genetic screens: Arabidopsis thaliana". Nature Reviews. Genetics. 3 (2): 124–136. doi:10.1038/nrg730. PMID 11836506. S2CID 431110.
^ St Johnston D (March 2002). "The art and design of genetic screens: Drosophila melanogaster". Nature Reviews. Genetics. 3 (3): 176–188. doi:10.1038/nrg751. PMID 11972155. S2CID 195368351.
^ Jorgensen EM, Mango SE (May 2002). "The art and design of genetic screens: caenorhabditis elegans". Nature Reviews. Genetics. 3 (5): 356–369. doi:10.1038/nrg794. PMID 11988761. S2CID 152517.
^ Casselton L, Zolan M (September 2002). "The art and design of genetic screens: filamentous fungi". Nature Reviews. Genetics. 3 (9): 683–697. doi:10.1038/nrg889. PMID 12209143. S2CID 11744977.

[Hartwell_2008-1] Hartwell LH, Hood L, Goldberg ML, Reynolds AE, Silver LM, Veres RC (2008). Genetics: from genes to genomes. Boston: McGraw-Hill Higher Education. ISBN 978-0-07-284846-5.

[Patton_2001-2] Patton EE, Zon LI (December 2001). "The art and design of genetic screens: zebrafish". Nature Reviews. Genetics. 2 (12): 956–966. doi:10.1038/35103567. PMID 11733748. S2CID 3166016.

[Arabidopsis-3] Page DR, Grossniklaus U (February 2002). "The art and design of genetic screens: Arabidopsis thaliana". Nature Reviews. Genetics. 3 (2): 124–136. doi:10.1038/nrg730. PMID 11836506. S2CID 431110.

[St_Johnston_2002-4] St Johnston D (March 2002). "The art and design of genetic screens: Drosophila melanogaster". Nature Reviews. Genetics. 3 (3): 176–188. doi:10.1038/nrg751. PMID 11972155. S2CID 195368351.

[Jorgensen_2002-5] Jorgensen EM, Mango SE (May 2002). "The art and design of genetic screens: caenorhabditis elegans". Nature Reviews. Genetics. 3 (5): 356–369. doi:10.1038/nrg794. PMID 11988761. S2CID 152517.

[Casselton_2002-6] Casselton L, Zolan M (September 2002). "The art and design of genetic screens: filamentous fungi". Nature Reviews. Genetics. 3 (9): 683–697. doi:10.1038/nrg889. PMID 12209143. S2CID 11744977.

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