Gilbert Stork

Gilbert Stork
Born(1921-12-31)31 December 1921
Died21 October 2017(2017-10-21) (aged 95)[1]
CitizenshipBelgium
United States
Alma materUniversity of Florida B.S. 1942
University of Wisconsin–Madison PhD 1945
AwardsACS Award in Pure Chemistry (1957)
William H. Nichols Medal (1980)
NAS Award in Chemical Sciences (1982)
National Medal of Science (1982)
Wolf Prize (1996)
The Ryoji Noyori Prize (2003)
Scientific career
InstitutionsHarvard University
Columbia University
ThesisThe synthesis of 3,4-disubstituted piperidines (1945)
Doctoral advisorSamuel M. McElvain
Notable students

Gilbert Stork (December 31, 1921 – October 21, 2017)[2] was an organic chemist. For a quarter of a century he was the Eugene Higgins Professor of Chemistry Emeritus at Columbia University.[3] He is known for making significant contributions to the total synthesis of natural products, including a lifelong fascination with the synthesis of quinine. In so doing he also made a number of contributions to mechanistic understanding of reactions, and performed pioneering work on enamine chemistry, leading to development of the Stork enamine alkylation.[3]: 111 [4] It is believed he was responsible for the first planned stereocontrolled synthesis as well as the first natural product to be synthesised with high stereoselectivity.[5]

Stork was also an accomplished mentor of young chemists and many of his students have gone on to make significant contributions in their own right.

  1. ^ Wender, Paul A. (2017). "Gilbert Stork (1921–2017)". Nature. 551 (7682): 566. doi:10.1038/d41586-017-07527-8. PMID 29189811.
  2. ^ Nakamura, Eiichi; Winkler, Jeffrey D.; Aggarwal, Varinder K. (2018). "Gilbert Stork (1921–2017)". Angewandte Chemie International Edition. 57 (1): 36. doi:10.1002/anie.201711474. ISSN 1521-3773. PMID 29193592. S2CID 1109751.
  3. ^ a b Hargittai, István; Hargittai, Magdolna (2003). More conversations with famous chemists ([Verschiedene Aufl.] ed.). London: Imperial College Press. pp. 109–119. ISBN 978-1-86094-336-2. Retrieved December 1, 2016.
  4. ^ Stork, Gilbert; Terrell, Ross; Szmuszkovicz, Jacob (April 1954). "A New Synthesis of 2-Alkyl and 2-Acyl Ketones". Journal of the American Chemical Society. 76 (7): 2029–2030. doi:10.1021/ja01636a103.
  5. ^ Seeman, Jeffrey I. (March 19, 2012). "Gilbert Stork: In His Own Words and in the Musings of His Friends". Angewandte Chemie International Edition. 51 (12): 3012–3023. doi:10.1002/anie.201200033. ISSN 1521-3773. PMID 22383434. S2CID 42348686.

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