Glanzmann's thrombasthenia

Glanzmann's thrombasthenia
Other namesThrombasthenia of Glanzmann and Naegeli[1]
This condition is inherited in a autosomal recessive manner
SpecialtyHematology Edit this on Wikidata

Glanzmann's thrombasthenia is an abnormality of the platelets.[2] It is an extremely rare coagulopathy (bleeding disorder due to a blood abnormality), in which the platelets contain defective or low levels of glycoprotein IIb/IIIa (GpIIb/IIIa), which is a receptor for fibrinogen. As a result, no fibrinogen bridging of platelets to other platelets can occur, and the bleeding time is significantly prolonged.

  1. ^ "Glanzmann thrombasthenia | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program". rarediseases.info.nih.gov. Archived from the original on 30 October 2019. Retrieved 30 October 2019.
  2. ^ "Glanzmann thrombasthenia" at Dorland's Medical Dictionary

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