HIV vaccine development

An HIV vaccine is a potential vaccine that could be either a preventive vaccine or a therapeutic vaccine, which means it would either protect individuals from being infected with HIV or treat HIV-infected individuals.

It is thought that an HIV vaccine could either induce an immune response against HIV (active vaccination approach) or consist of preformed antibodies against HIV (passive vaccination approach).^[1]

Two active vaccine regimens, studied in the RV 144 and Imbokodo trials, showed they can prevent HIV in some individuals.

However, the protection was in relatively few individuals, and was not long lasting. For these reasons, no HIV vaccines have been licensed for the market yet.

^ Gray GE, Laher F, Lazarus E, Ensoli B, Corey L (April 2016). "Approaches to preventative and therapeutic HIV vaccines". Current Opinion in Virology. 17: 104–109. doi:10.1016/j.coviro.2016.02.010. PMC 5020417. PMID 26985884.

[1] Gray GE, Laher F, Lazarus E, Ensoli B, Corey L (April 2016). "Approaches to preventative and therapeutic HIV vaccines". Current Opinion in Virology. 17: 104–109. doi:10.1016/j.coviro.2016.02.010. PMC 5020417. PMID 26985884.

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