Back هيو هكسلي Arabic هيو هكسلى ARZ Hugh Huxley Czech Hugh Huxley Danish Hugh Esmor Huxley German Hugh Huxley Spanish هیو هاکسلی Persian Hugh Huxley French Hugh Huxley Italian Hugh Huxley Dutch
Hugh Huxley | |
|---|---|
 | |
| Born | Hugh Esmor Huxley 25 February 1924 Birkenhead, Cheshire, England |
| Died | 25 July 2013 (aged 89) |
| Alma mater | Christ's College, Cambridge Cambridge University (PhD) |
| Known for | Muscle contraction Muscle proteins |
| Spouse | Frances Huxley |
| Awards | William Bate Hardy Prize (1966) Louisa Gross Horwitz Prize (1971) Royal Medal (1977) E.B. Wilson Medal (1983) Albert Einstein World Award of Science (1987) Franklin Medal (1990) Copley Medal (1997) |
| Scientific career | |
| Fields | Molecular Biologist |
| Institutions | Massachusetts Institute of Technology University College London MRC Laboratory of Molecular Biology Brandeis University |
| Doctoral advisor | John Kendrew |
| Military career | |
| Allegiance |  United Kingdom |
| Service/ |  Royal Air Force(RAFVR) |
| Years of service | 1943–1947 |
| Rank | Flight Lieutenant |
| Battles/wars | Second World War |
| Awards | Member of the Order of the British Empire (MBE, Military Division) |
Hugh Esmor Huxley MBE FRS (25 February 1924 – 25 July 2013) was a British molecular biologist who made important discoveries in the physiology of muscle.[1][2][3][4][5][6] He was a graduate in physics from Christ's College, Cambridge. However, his education was interrupted for five years by the Second World War, during which he served in the Royal Air Force. His contribution to development of radar earned him an MBE.
Huxley was the first PhD student of Laboratory of Molecular Biology of the Medical Research Council at Cambridge, where he worked on X-ray diffraction studies on muscle fibres. In the 1950s he was one of the first to use electron microscopy to study biological specimens. During his postdoctoral at Massachusetts Institute of Technology, he, with fellow researcher Jean Hanson, discovered the underlying principle of muscle movement, popularised as the sliding filament theory in 1954. After 15 years of research, he proposed the "swinging cross-bridge hypothesis" in 1969, which became modern understanding of the molecular basis of muscle contraction, and much of other cellular motility.[7][8]
Huxley worked at University College London for seven years, and at Laboratory of Molecular Biology for fifteen years, where he was its Deputy Director from 1979. Between 1987 and 1997, he was professor at Brandeis University in Massachusetts, where he spent the rest of his life as emeritus professor.
- ^ Holmes, K. C. (2013). "Hugh Esmor Huxley (1924-2013)". Proceedings of the National Academy of Sciences USA. 110 (46): 18344–18345. Bibcode:2013PNAS..11018344H. doi:10.1073/pnas.1318966110. PMC 3832017. PMID 24173032.
- ^ "Professor Hugh Esmor Huxley MBE FRS | Christs College Cambridge". Christs.cam.ac.uk. 25 July 2013. Archived from the original on 16 September 2013. Retrieved 31 July 2013.
- ^ The Official Site of Louisa Gross Horwitz Prize
- ^ Hugh Huxley, editor "Memories and Consequences: Visiting Scientists at the MRC Laboratory of Molecular Biology, Cambridge", Medical Research Council, 2013, ISBN 978-184831-646-1. This book is collection of 41 essays by some of the many visiting scientists to the MRC LMB in Cambridge, England, during the period 1957-1986.
- ^ John Finch; 'A Nobel Fellow On Every Floor', Medical Research Council 2008, 381 pp, ISBN 978-1-84046-940-0; this book is all about the MRC Laboratory of Molecular Biology, Cambridge.
- ^ Weeds, Alan (2013). "Hugh Huxley (1924–2013)". Nature. 500 (7464): 530. Bibcode:2013Natur.500..530W. doi:10.1038/500530a. PMID 23985864.
- ^ Weber, A (2002). "Hugh E. Huxley: birth of the filament sliding model of muscle contraction". Trends in Cell Biology. 12 (5): 243–245. doi:10.1016/S0962-8924(02)02270-5. PMID 12062173.
- ^ Pollard, Thomas D.; Goldman, Yale E. (2013). "Remembrance of Hugh E. Huxley, a founder of our field". Cytoskeleton. 70 (9): 471–475. doi:10.1002/cm.21141. PMID 24106169. S2CID 10035669.
© MMXXIII Rich X Search. We shall prevail. All rights reserved. Rich X Search