IFNAR1

IFNAR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3S98, 3SE3, 3SE4, 4PO6
Identifiers
Aliases	IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, interferon alpha and beta receptor subunit 1
External IDs	OMIM: 107450; MGI: 107658; HomoloGene: 524; GeneCards: IFNAR1; OMA:IFNAR1 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	33,359,864 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	91,304,329 bp
RNA expression pattern
	Top expressed in
	monocyte; ; rectum; ; gallbladder; ; ventricular zone; ; islet of Langerhans; ; endothelial cell; ; Achilles tendon; ; blood; ; epithelium of colon; ; stromal cell of endometrium;
	Top expressed in
	genital tubercle; ; tail of embryo; ; granulocyte; ; Rostral migratory stream; ; vas deferens; ; aortic valve; ; stroma of bone marrow; ; cumulus cell; ; thymus; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	interferon receptor activity; protein binding; interleukin-10 receptor activity; type I interferon receptor activity; type I interferon binding; cytokine receptor activity;
Cellular component	integral component of membrane; endosome; late endosome; membrane; plasma membrane; lysosome; integral component of plasma membrane;
Biological process	receptor signaling pathway via JAK-STAT; response to virus; cytokine-mediated signaling pathway; response to lipopolysaccharide; cellular response to interferon-alpha; type I interferon signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3454
	15975
	ENSG00000142166
	ENSMUSG00000022967
	P17181
	P33896
	NM_000629
	NM_010508
	NP_000620
	NP_034638
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000142166 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022967 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Novick D, Cohen B, Rubinstein M (Jun 1994). "The human interferon alpha/beta receptor: characterization and molecular cloning". Cell. 77 (3): 391–400. doi:10.1016/0092-8674(94)90154-6. PMID 8181059. S2CID 140206806.
^ "Entrez Gene: IFNAR1 interferon (alpha, beta and omega) receptor 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000142166 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022967 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8181059-5] Novick D, Cohen B, Rubinstein M (Jun 1994). "The human interferon alpha/beta receptor: characterization and molecular cloning". Cell. 77 (3): 391–400. doi:10.1016/0092-8674(94)90154-6. PMID 8181059. S2CID 140206806.

[entrez-6] "Entrez Gene: IFNAR1 interferon (alpha, beta and omega) receptor 1".

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