IFNAR2

IFNAR2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1N6U, 1N6V, 2HYM, 2KZ1, 2LAG, 3S8W, 3S9D, 3SE3, 3SE4
Identifiers
Aliases	IFNAR2, IFN-R, IFN-alpha-REC, IFNABR, IFNARB, IMD45, interferon alpha and beta receptor subunit 2
External IDs	OMIM: 602376; MGI: 1098243; HomoloGene: 49242; GeneCards: IFNAR2; OMA:IFNAR2 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	33,265,675 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	91,202,477 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; oocyte; ; granulocyte; ; trabecular bone; ; pylorus; ; cartilage tissue; ; lymph node; ; islet of Langerhans; ; spleen;
	Top expressed in
	granulocyte; ; right lobe of liver; ; right kidney; ; tail of embryo; ; genital tubercle; ; spleen; ; thymus; ; mesenteric lymph nodes; ; internal carotid artery; ; bone marrow;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; type I interferon binding; protein kinase binding; type I interferon receptor activity; cytokine receptor activity;
Cellular component	integral component of membrane; extracellular region; plasma membrane; integral component of plasma membrane; membrane; intracellular anatomical structure; extracellular space;
Biological process	cell surface receptor signaling pathway; response to virus; receptor signaling pathway via JAK-STAT; regulation of type I interferon-mediated signaling pathway; type I interferon signaling pathway; response to interferon-alpha; response to interferon-beta; defense response to virus; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3455
	15976
	ENSG00000159110
	ENSMUSG00000022971
	P48551
	O35664
NM_207585; NM_000874; NM_001289125; NM_001289126; NM_001289128;
	NM_207584; NM_001385054; NM_001385055
	NM_001110498; NM_010509; NM_001347258
NP_000865; NP_001276054; NP_001276055; NP_001276057; NP_997467;
	NP_997468
	NP_001103968; NP_001334187; NP_034639
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon-alpha/beta receptor beta chain is a protein that in humans is encoded by the IFNAR2 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000159110 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022971 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Novick D, Cohen B, Rubinstein M (June 1994). "The human interferon alpha/beta receptor: characterization and molecular cloning". Cell. 77 (3): 391–400. doi:10.1016/0092-8674(94)90154-6. PMID 8181059. S2CID 140206806.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000159110 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022971 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8181059-5] Novick D, Cohen B, Rubinstein M (June 1994). "The human interferon alpha/beta receptor: characterization and molecular cloning". Cell. 77 (3): 391–400. doi:10.1016/0092-8674(94)90154-6. PMID 8181059. S2CID 140206806.

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