IL2RB

IL2RB
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2B5I, 2ERJ, 3QAZ, 4GS7
Identifiers
Aliases	IL2RB, CD122, IL15RB, P70-75, interleukin 2 receptor subunit beta, IMD63
External IDs	OMIM: 146710; MGI: 96550; HomoloGene: 47955; GeneCards: IL2RB; OMA:IL2RB - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	37,175,054 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	78,379,471 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; decidua; ; mucosa of ileum; ; blood; ; lymph node; ; spleen; ; appendix; ; bone marrow cells; ; mucosa of urinary bladder; ; epithelium of nasopharynx;
	Top expressed in
	mesenteric lymph nodes; ; blood; ; decidua; ; spleen; ; secondary oocyte; ; gastrula; ; zygote; ; thymus; ; pharynx; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	interleukin-2 binding; protein binding; cytokine receptor activity; interleukin-2 receptor activity; interleukin-15 receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; external side of plasma membrane; endosome; cytosol; interleukin-2 receptor complex; cell surface;
Biological process	negative regulation of apoptotic process; MAPK cascade; interleukin-2-mediated signaling pathway; viral process; signal transduction; cytokine-mediated signaling pathway; interleukin-15-mediated signaling pathway; regulation of molecular function; positive regulation of phagocytosis; protein-containing complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	3560
	16185
	ENSG00000100385
	ENSMUSG00000068227
	P14784
	P16297
	NM_000878; NM_001346222; NM_001346223
	NM_008368
	NP_000869; NP_001333151; NP_001333152
	NP_032394
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-2 receptor subunit beta is a protein that in humans is encoded by the IL2RB gene.^[5] Also known as CD122; IL15RB; P70-75.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100385 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068227 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: IL2RB interleukin 2 receptor, beta".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000100385 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068227 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: IL2RB interleukin 2 receptor, beta".

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