Interleukin 25

IL25
Identifiers
Aliases	IL25, IL17E, IL-25, interleukin 25
External IDs	OMIM: 605658; MGI: 2155888; HomoloGene: 15429; GeneCards: IL25; OMA:IL25 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	23,376,403 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,173,294 bp
RNA expression pattern
	Top expressed in
	testicle; ; right auricle; ; human musculoskeletal system; ; muscular system; ; skeletal muscle; ; gastrocnemius muscle; ; thigh; ; muscle of thigh; ; ventricle; ; left ventricle;
	Top expressed in
	embryo; ; embryo; ; embryo; ; neural tube; ; placenta; ; olfactory bulb; ; diencephalon; ; gland; ; endocrine gland; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	interleukin-17E receptor binding; cytokine activity;
Cellular component	extracellular region; extracellular space;
Biological process	response to fungus; interleukin-13 production; response to nematode; inflammatory response to antigenic stimulus; eosinophil differentiation; positive regulation of transcription by RNA polymerase II; interleukin-5 production; inflammatory response; regulation of signaling receptor activity; biological process; interleukin-17-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	64806
	140806
	ENSG00000166090
	ENSMUSG00000040770
	Q9H293
	Q8VHH8
	NM_172314; NM_022789
	NM_080729
	NP_073626; NP_758525
	NP_542767
	Wikidata
View/Edit Human	View/Edit Mouse

Interleukin-25 (IL-25) – also known as interleukin-17E (IL-17E)^[5] – is a protein that in humans is encoded by the IL25 gene on chromosome 14.^[6]^[7]^[8] IL-25 was discovered in 2001 and is made up of 177 amino acids.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166090 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040770 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Product reference for IL-17E
^ ^a ^b Lee J, Ho WH, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI, Gurney AL (January 2001). "IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1". The Journal of Biological Chemistry. 276 (2): 1660–4. doi:10.1074/jbc.M008289200. PMID 11058597.
^ Cite error: The named reference :1 was invoked but never defined (see the help page).
^ "Entrez Gene: IL25 interleukin 25".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166090 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000040770 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Product reference for IL-17E

[:0-6] Lee J, Ho WH, Maruoka M, Corpuz RT, Baldwin DT, Foster JS, Goddard AD, Yansura DG, Vandlen RL, Wood WI, Gurney AL (January 2001). "IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1". The Journal of Biological Chemistry. 276 (2): 1660–4. doi:10.1074/jbc.M008289200. PMID 11058597.

[:1-7] Cite error: The named reference :1 was invoked but never defined (see the help page).

[entrez-8] "Entrez Gene: IL25 interleukin 25".

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