Isotopes are any of the several different forms of an element each having different atomic mass (mass number).
Isotope can also refer to:
- Isotope (band), a British jazz-rock band (1972–1976)
- Isotope (album), a 1983 album by jazz pianist Kirk Lightsey
- Isotope (catamaran), an American sailboat design
- Albuquerque Isotopes, a minor league baseball team of the Pacific Coast League
- Springfield Isotopes, a fictional baseball team in the TV show The Simpsons
- Isotopes Punk Rock Baseball Club, a Canadian baseball-themed punk rock band
- Isotope 217, a jazz band from Chicago, United States
- Isotope 244, a video game developer based in the USA
- Isotope (Jordan algebra) in mathematics, a method of modifying the product on a Jordan algebra
- An isotope of an algebra: see Isotopy of algebras
- An isotope of a loop or quasigroup: see Isotopy of loops
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