James Black (pharmacologist)

Sir James Black
Born
James Whyte Black

(1924-06-14)14 June 1924
Died22 March 2010(2010-03-22) (aged 85)
London, England
NationalityBritish
CitizenshipUnited Kingdom
Alma materUniversity of St Andrews
Known forwork towards the use of propranolol and cimetidine
Awards
Scientific career
FieldsPharmacology
Institutions
Websitewww.nobelprize.org/nobel_prizes/medicine/laureates/1988/black-bio.html

Sir James Whyte Black OM FRS FRSE FRCP (14 June 1924 – 22 March 2010[2]) was a Scottish physician and pharmacologist. Together with Gertrude B. Elion and George H. Hitchings, he shared the Nobel Prize for Medicine in 1988 for pioneering strategies for rational drug-design, which, in his case, lead to the development of propranolol and cimetidine.[3][4] Black established a Veterinary Physiology department at the University of Glasgow, where he became interested in the effects of adrenaline on the human heart. He went to work for ICI Pharmaceuticals in 1958 and, while there, developed propranolol, a beta blocker used for the treatment of heart disease.[5] Black was also responsible for the development of cimetidine, an H2 receptor antagonist, a drug used to treat stomach ulcers.

  1. ^ Cite error: The named reference frs was invoked but never defined (see the help page).
  2. ^ Cite error: The named reference ObitSTV was invoked but never defined (see the help page).
  3. ^ Cite error: The named reference nobel was invoked but never defined (see the help page).
  4. ^ James Black tells his life story at Web of Stories
  5. ^ Black JW, Crowther AF, Shanks RG, Smith LH, Dornhorst AC (1964). "A new adrenergic betareceptor antagonist". The Lancet. 283 (7342): 1080–1081. doi:10.1016/S0140-6736(64)91275-9. PMID 14132613.

© MMXXIII Rich X Search. We shall prevail. All rights reserved. Rich X Search