KIR2DL4

KIR2DL4
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	3WYR
Identifiers
Aliases	KIR2DL4, CD158D, G9P, KIR-103AS, KIR103, KIR103AS, KIR, KIR-2DL4, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4
External IDs	OMIM: 604945; HomoloGene: 124412; GeneCards: KIR2DL4; OMA:KIR2DL4 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	54,814,517 bp
RNA expression pattern
	Top expressed in
	testicle; ; spleen; ; granulocyte; ; mucosa of transverse colon; ; blood; ; right lung; ; rectum; ; duodenum; ; epithelium of colon; ; appendix;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; transmembrane signaling receptor activity; MHC class Ib receptor activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; endosome; early endosome membrane;
Biological process	cellular defense response; signal transduction; regulation of immune response; positive regulation of natural killer cell cytokine production; negative regulation of natural killer cell mediated cytotoxicity; positive regulation of cellular senescence;
	Sources:Amigo / QuickGO
Orthologs
	3805
	n/a
ENSG00000274945; ENSG00000278606; ENSG00000277540; ENSG00000273575; ENSG00000275732;
	ENSG00000275699; ENSG00000275317; ENSG00000284509; ENSG00000277750; ENSG00000284365; ENSG00000275848; ENSG00000275456; ENSG00000274955; ENSG00000277964; ENSG00000277362; ENSG00000276979; ENSG00000283961; ENSG00000277850; ENSG00000284460; ENSG00000278074; ENSG00000277076; ENSG00000274189; ENSG00000276044; ENSG00000276779; ENSG00000277355; ENSG00000283869; ENSG00000278201; ENSG00000278271; ENSG00000275237; ENSG00000189013; ENSG00000273498; ENSG00000274193; ENSG00000278430; ENSG00000274232; ENSG00000274609; ENSG00000284013; ENSG00000283986; ENSG00000284340; ENSG00000284562; ENSG00000284206; ENSG00000284457
	n/a
	Q99706
	n/a
	NM_002255; NM_001080770; NM_001080772; NM_001258383
	n/a
	NP_001074239; NP_001074241; NP_002246
	n/a
	Wikidata
View/Edit Human

Killer cell immunoglobulin-like receptor 2DL4 is a protein that in humans is encoded by the KIR2DL4 gene.^[3]^[4]

^ ^a ^b ^c ENSG00000278606, ENSG00000277540, ENSG00000273575, ENSG00000275732, ENSG00000275699, ENSG00000275317, ENSG00000284509, ENSG00000277750, ENSG00000284365, ENSG00000275848, ENSG00000275456, ENSG00000274955, ENSG00000277964, ENSG00000277362, ENSG00000276979, ENSG00000283961, ENSG00000277850, ENSG00000284460, ENSG00000278074, ENSG00000277076, ENSG00000274189, ENSG00000276044, ENSG00000276779, ENSG00000277355, ENSG00000283869, ENSG00000278201, ENSG00000278271, ENSG00000275237, ENSG00000189013, ENSG00000273498, ENSG00000274193, ENSG00000278430, ENSG00000274232, ENSG00000274609, ENSG00000284013, ENSG00000283986, ENSG00000284340, ENSG00000284562, ENSG00000284206, ENSG00000284457 GRCh38: Ensembl release 89: ENSG00000274945, ENSG00000278606, ENSG00000277540, ENSG00000273575, ENSG00000275732, ENSG00000275699, ENSG00000275317, ENSG00000284509, ENSG00000277750, ENSG00000284365, ENSG00000275848, ENSG00000275456, ENSG00000274955, ENSG00000277964, ENSG00000277362, ENSG00000276979, ENSG00000283961, ENSG00000277850, ENSG00000284460, ENSG00000278074, ENSG00000277076, ENSG00000274189, ENSG00000276044, ENSG00000276779, ENSG00000277355, ENSG00000283869, ENSG00000278201, ENSG00000278271, ENSG00000275237, ENSG00000189013, ENSG00000273498, ENSG00000274193, ENSG00000278430, ENSG00000274232, ENSG00000274609, ENSG00000284013, ENSG00000283986, ENSG00000284340, ENSG00000284562, ENSG00000284206, ENSG00000284457 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Selvakumar A, Steffens U, Dupont B (October 1996). "NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains". Tissue Antigens. 48 (4 Pt 1): 285–94. doi:10.1111/j.1399-0039.1996.tb02647.x. PMID 8946682.
^ "Entrez Gene: KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4".

[refGRCh38Ensembl-1] ENSG00000278606, ENSG00000277540, ENSG00000273575, ENSG00000275732, ENSG00000275699, ENSG00000275317, ENSG00000284509, ENSG00000277750, ENSG00000284365, ENSG00000275848, ENSG00000275456, ENSG00000274955, ENSG00000277964, ENSG00000277362, ENSG00000276979, ENSG00000283961, ENSG00000277850, ENSG00000284460, ENSG00000278074, ENSG00000277076, ENSG00000274189, ENSG00000276044, ENSG00000276779, ENSG00000277355, ENSG00000283869, ENSG00000278201, ENSG00000278271, ENSG00000275237, ENSG00000189013, ENSG00000273498, ENSG00000274193, ENSG00000278430, ENSG00000274232, ENSG00000274609, ENSG00000284013, ENSG00000283986, ENSG00000284340, ENSG00000284562, ENSG00000284206, ENSG00000284457 GRCh38: Ensembl release 89: ENSG00000274945, ENSG00000278606, ENSG00000277540, ENSG00000273575, ENSG00000275732, ENSG00000275699, ENSG00000275317, ENSG00000284509, ENSG00000277750, ENSG00000284365, ENSG00000275848, ENSG00000275456, ENSG00000274955, ENSG00000277964, ENSG00000277362, ENSG00000276979, ENSG00000283961, ENSG00000277850, ENSG00000284460, ENSG00000278074, ENSG00000277076, ENSG00000274189, ENSG00000276044, ENSG00000276779, ENSG00000277355, ENSG00000283869, ENSG00000278201, ENSG00000278271, ENSG00000275237, ENSG00000189013, ENSG00000273498, ENSG00000274193, ENSG00000278430, ENSG00000274232, ENSG00000274609, ENSG00000284013, ENSG00000283986, ENSG00000284340, ENSG00000284562, ENSG00000284206, ENSG00000284457 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8946682-3] Selvakumar A, Steffens U, Dupont B (October 1996). "NK cell receptor gene of the KIR family with two IG domains but highest homology to KIR receptors with three IG domains". Tissue Antigens. 48 (4 Pt 1): 285–94. doi:10.1111/j.1399-0039.1996.tb02647.x. PMID 8946682.

[entrez-4] "Entrez Gene: KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4".

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