LAIR1

LAIR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3KGR, 3RP1
Identifiers
Aliases	LAIR1, CD305, LAIR-1, leukocyte associated immunoglobulin like receptor 1
External IDs	OMIM: 602992; MGI: 105492; HomoloGene: 48097; GeneCards: LAIR1; OMA:LAIR1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	54,370,558 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	4,066,203 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; appendix; ; monocyte; ; spleen; ; blood; ; lymph node; ; bone marrow; ; right lung; ; placenta; ; upper lobe of left lung;
	Top expressed in
	granulocyte; ; spleen; ; stroma of bone marrow; ; zygote; ; mesenteric lymph nodes; ; secondary oocyte; ; lumbar subsegment of spinal cord; ; blood; ; supraoptic nucleus; ; thymus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; plasma membrane; membrane; specific granule membrane; tertiary granule membrane;
Biological process	adaptive immune response; regulation of immune response; immune system process; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	3903
	52855
ENSG00000276053; ENSG00000276163; ENSG00000278154; ENSG00000274110; ENSG00000167613;
	n/a
	ENSMUSG00000055541
	Q6GTX8
	Q8BG84
NM_001289023; NM_001289025; NM_001289026; NM_001289027; NM_002287;
	NM_021706; NM_021708
NM_001113474; NM_178611; NM_001302675; NM_001302676; NM_001302677;
	NM_001302681; NM_001302682; NM_001302683
NP_001275952; NP_001275954; NP_001275955; NP_001275956; NP_002278;
	NP_068352
NP_001106945; NP_001289604; NP_001289605; NP_001289606; NP_001289610;
	NP_001289611; NP_001289612; NP_848726
	Wikidata
View/Edit Human	View/Edit Mouse

Leukocyte-associated immunoglobulin-like receptor 1 is a protein that in humans is encoded by the LAIR1 gene.^[5]^[6] LAIR1 has also been designated as CD305 (cluster of differentiation 305).

^ ^a ^b ^c ENSG00000276163, ENSG00000278154, ENSG00000274110, ENSG00000167613 GRCh38: Ensembl release 89: ENSG00000276053, ENSG00000276163, ENSG00000278154, ENSG00000274110, ENSG00000167613 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000055541 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Meyaard L, Adema GJ, Chang C, Woollatt E, Sutherland GR, Lanier LL, Phillips JH (September 1997). "LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes". Immunity. 7 (2): 283–90. doi:10.1016/S1074-7613(00)80530-0. hdl:2066/26173. PMID 9285412.
^ "Entrez Gene: LAIR1 leukocyte-associated immunoglobulin-like receptor 1".

[refGRCh38Ensembl-1] ENSG00000276163, ENSG00000278154, ENSG00000274110, ENSG00000167613 GRCh38: Ensembl release 89: ENSG00000276053, ENSG00000276163, ENSG00000278154, ENSG00000274110, ENSG00000167613 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000055541 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9285412-5] Meyaard L, Adema GJ, Chang C, Woollatt E, Sutherland GR, Lanier LL, Phillips JH (September 1997). "LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes". Immunity. 7 (2): 283–90. doi:10.1016/S1074-7613(00)80530-0. hdl:2066/26173. PMID 9285412.

[entrez-6] "Entrez Gene: LAIR1 leukocyte-associated immunoglobulin-like receptor 1".

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