Letovirinae

Letovirinae
Virus classification
(unranked):	Virus
Realm:	Riboviria
Kingdom:	Orthornavirae
Phylum:	Pisuviricota
Class:	Pisoniviricetes
Order:	Nidovirales
Family:	Coronaviridae
Subfamily:	Letovirinae
Lower taxa
	Genus: Alphaletovirus; Subgenus: Milecovirus; Species: Alphaletovirus microhylae;

Letovirinae is a subfamily of viruses within the family Coronaviridae, where it is the only subfamily besides the more diverse Orthocoronavirinae (coronaviruses). Letovirinae contains one genus, Alphaletovirus, which contains one subgenus, Milecovirus, which contains one species, Microhyla letovirus 1 (MLeV, Alphaletovirus microhylae).^[1]^[2] This species was discovered in 2018 and is hosted by the ornate chorus frog (Microhyla fissipes).

Other unaccepted species in the Letovirinae have been discovered in Pacific salmon (Oncorhynchus), and in Murray River carp (Cyprinus).^[3]^[4]^[5]

^ "Virus Taxonomy: 2024 Release". International Committee on Taxonomy of Viruses. Retrieved 4 April 2025.
^ "Species List: Coronaviridae". International Committee on Taxonomy of Viruses. Retrieved 4 April 2025.
^ Mordecai GJ, Miller KM, Di Cicco E, Schulze AD, Kaukinen KH, Ming TJ, Li S, Tabata A, Teffer A, Patterson DA, Ferguson HW, Suttle CA (2019). "Endangered wild salmon infected by newly discovered viruses" (PDF). eLife. 8: e47615. doi:10.7554/eLife.47615.001. PMC 6721791. PMID 31478480.
^ Costa, Vincenzo A.; Mifsud, Jonathon C. O.; Gilligan, Dean; Williamson, Jane E.; Holmes, Edward C.; Geoghegan, Jemma L. (2021-02-25). "Metagenomic sequencing reveals a lack of virus exchange between native and invasive freshwater fish across the Murray-Darling Basin, Australia". bioRxiv: 2021.02.25.432824. doi:10.1101/2021.02.25.432824. S2CID 232081778.
^ Costa, Vincenzo A.; Mifsud, Jonathon C. O.; Gilligan, Dean; Williamson, Jane E.; Holmes, Edward C.; Geoghegan, Jemma L. (January 2021). "Metagenomic sequencing reveals a lack of virus exchange between native and invasive freshwater fish across the Murray-Darling Basin, Australia". Virus Evolution. 7 (1): veab034. doi:10.1093/ve/veab034. ISSN 2057-1577. PMC 8121191. PMID 34017611.

[1] "Virus Taxonomy: 2024 Release". International Committee on Taxonomy of Viruses. Retrieved 4 April 2025.

[2] "Species List: Coronaviridae". International Committee on Taxonomy of Viruses. Retrieved 4 April 2025.

[3] Mordecai GJ, Miller KM, Di Cicco E, Schulze AD, Kaukinen KH, Ming TJ, Li S, Tabata A, Teffer A, Patterson DA, Ferguson HW, Suttle CA (2019). "Endangered wild salmon infected by newly discovered viruses" (PDF). eLife. 8: e47615. doi:10.7554/eLife.47615.001. PMC 6721791. PMID 31478480.

[4] Costa, Vincenzo A.; Mifsud, Jonathon C. O.; Gilligan, Dean; Williamson, Jane E.; Holmes, Edward C.; Geoghegan, Jemma L. (2021-02-25). "Metagenomic sequencing reveals a lack of virus exchange between native and invasive freshwater fish across the Murray-Darling Basin, Australia". bioRxiv: 2021.02.25.432824. doi:10.1101/2021.02.25.432824. S2CID 232081778.

[5] Costa, Vincenzo A.; Mifsud, Jonathon C. O.; Gilligan, Dean; Williamson, Jane E.; Holmes, Edward C.; Geoghegan, Jemma L. (January 2021). "Metagenomic sequencing reveals a lack of virus exchange between native and invasive freshwater fish across the Murray-Darling Basin, Australia". Virus Evolution. 7 (1): veab034. doi:10.1093/ve/veab034. ISSN 2057-1577. PMC 8121191. PMID 34017611.

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