Mary F. Lyon

Mary Lyon
Lyon in 2010
Born
Mary Frances Lyon

(1925-05-15)15 May 1925[1]
Norwich, England
Died25 December 2014(2014-12-25) (aged 89)[3]
Alma materUniversity of Cambridge (BA, PhD)
Known forX-chromosome inactivation[4]
Awards
Scientific career
InstitutionsUniversity of Edinburgh
Doctoral advisorRonald Fisher
Doctoral studentsElizabeth Fisher[2]

Mary Frances Lyon FRS[5][6] (15 May 1925 – 25 December 2014)[3] was an English geneticist best known for her discovery of X-chromosome inactivation, an important biological phenomenon.[7][8][9][10][11][12][13]

  1. ^ a b Anon (2015). "Lyon, Mary Frances". Who's Who (online Oxford University Press ed.). A & C Black. doi:10.1093/ww/9780199540884.013.U25200. (Subscription or UK public library membership required.)
  2. ^ Fisher, Elizabeth Mary Claire (1987). Microcloning and molecular mapping of the mouse X chromosome. london.ac.uk (PhD thesis). University of London. hdl:10044/1/66999. OCLC 1103939662. EThOS uk.bl.ethos.769180. Free access icon
  3. ^ a b "Mary Lyon, geneticist – obituary". The Daily Telegraph. 3 February 2015. Retrieved 4 March 2015.
  4. ^ Lyon, M. F. (1998). "X-chromosome inactivation: A repeat hypothesis". Cytogenetics and Cell Genetics. 80 (1–4): 133–7. doi:10.1159/000014969. PMID 9678347. S2CID 46853044.
  5. ^ Fisher, Elizabeth; Rastan, Sohaila (2024). "Mary Frances Lyon. 15 May 1925 — 25 December 2014". Biographical Memoirs of Fellows of the Royal Society. 77.
  6. ^ "EC/1973/19: Lyon, Mary Frances". London: The Royal Society. Archived from the original on 8 July 2019.
  7. ^ Rastan, Sohaila (2015). "Mary F. Lyon (1925–2014) Grande dame of mouse genetics". Nature. 518 (7537): 36. doi:10.1038/518036a. PMID 25652989.
  8. ^ "Formal portrait of Mary Lyon by Godfrey Argent". London: The Royal Society. Archived from the original on 8 July 2019.
  9. ^ Mary Lyon Entry in Who named it?. Retrieved 4 March 2015.
  10. ^ Oakes, Elizabeth H. Lyon, Mary Frances. International Encyclopedia of Women Scientists. New York, NY. Facts on File, Inc. 2002. Facts on File, Inc. Science Online. factsonfile.com.
  11. ^ Lyon, M. F. (1961). "Gene action in the X-chromosome of the mouse (Mus musculus L.)". Nature. 190 (4773): 372–3. Bibcode:1961Natur.190..372L. doi:10.1038/190372a0. PMID 13764598. S2CID 4146768.
  12. ^ Brockdorff, Neil (2017). "Polycomb complexes in X chromosome inactivation". Philosophical Transactions of the Royal Society B. 372 (1733): 20170021. doi:10.1098/rstb.2017.0021. ISSN 0962-8436. PMC 5627167. PMID 28947664.
  13. ^ Heard, Edith; Brockdorff, Neil (2017). "Preface: X-chromosome inactivation and Mary Lyon". Philosophical Transactions of the Royal Society B. 372 (1733): 20160353. doi:10.1098/rstb.2016.0353. ISSN 0962-8436. PMC 5627156. PMID 28947653. Open access icon

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