Methedrone

Methedrone
Clinical data
ATC code	none;
Legal status
Legal status	DE: Anlage II (Authorized trade only, not prescriptible); UK: Class B; I-P(Poland);
Pharmacokinetic data
Elimination half-life	26.2±0.7 (h)
Identifiers
	IUPAC name (RS)-1-(4-Methoxyphenyl)-2-(methylamino)propan-1-one;
CAS Number	530-54-1 ;
PubChem CID	216281;
ChemSpider	187475 ;
UNII	L7HY239I58;
CompTox Dashboard (EPA)	DTXSID20862127 ;
ECHA InfoCard	100.209.920
Chemical and physical data
Formula	C11H15NO2
Molar mass	193.246 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES O=C(c1ccc(OC)cc1)C(NC)C;
	InChI InChI=1S/C11H15NO2/c1-8(12-2)11(13)9-4-6-10(14-3)7-5-9/h4-8,12H,1-3H3 ; Key:MQUIHBQDYYAEMH-UHFFFAOYSA-N ;
	(verify)

Methedrone (para-methoxymethcathinone, 4-methoxymethcathinone, bk-PMMA, PMMC, methoxyphedrine, 4-MeOMC) is a recreational drug of the cathinone chemical class.^[2] Chemically, methedrone is closely related to para-methoxymethamphetamine (PMMA), methylone and mephedrone. Methedrone received media attention in 2009 after the death of two young Swedish men. In both cases toxicology analysis showed methedrone was the only drug present in both men during the time of their overdose and subsequent deaths.^[3]^[4]

^ "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii (Dz.U. 2011 nr 105 poz. 614)". Internetowy System Aktów Prawnych. Retrieved 17 June 2011.
^ "Cathinone and its analogues (e.g. mephedrone, methedrone, α- pyrrolidinovalerophenone)". World Anti-Doping Agency. Archived from the original on 2014-11-06.
^ Wikström M, Thelander G, Nyström I, Kronstrand R (November 2010). "Two fatal intoxications with the new designer drug methedrone (4-methoxymethcathinone)". Journal of Analytical Toxicology. 34 (9): 594–8. doi:10.1093/jat/34.9.594. PMID 21073814.
^ "EMCDDA and Europol step up information collection on mephedrone". Drugnet Europe. No. online 69. January–March 2010. Retrieved May 21, 2018.

[1] "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii (Dz.U. 2011 nr 105 poz. 614)". Internetowy System Aktów Prawnych. Retrieved 17 June 2011.

[WADA-2] "Cathinone and its analogues (e.g. mephedrone, methedrone, α- pyrrolidinovalerophenone)". World Anti-Doping Agency. Archived from the original on 2014-11-06.

[wikstom2010-3] Wikström M, Thelander G, Nyström I, Kronstrand R (November 2010). "Two fatal intoxications with the new designer drug methedrone (4-methoxymethcathinone)". Journal of Analytical Toxicology. 34 (9): 594–8. doi:10.1093/jat/34.9.594. PMID 21073814.

[4] "EMCDDA and Europol step up information collection on mephedrone". Drugnet Europe. No. online 69. January–March 2010. Retrieved May 21, 2018.

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Clinical data

ATC code	none
Legal status
Legal status	DE: Anlage II (Authorized trade only, not prescriptible) UK: Class B I-P(Poland)^[1]
Pharmacokinetic data
Elimination half-life	26.2±0.7 (h)
Identifiers
IUPAC name (RS)-1-(4-Methoxyphenyl)-2-(methylamino)propan-1-one
CAS Number	530-54-1^Y
PubChem CID	216281
ChemSpider	187475^Y
UNII	L7HY239I58
CompTox Dashboard (EPA)	DTXSID20862127
ECHA InfoCard	100.209.920
Chemical and physical data
Formula	C₁₁H₁₅NO₂
Molar mass	193.246 g·mol⁻¹
3D model (JSmol)	Interactive image
Chirality	Racemic mixture
SMILES O=C(c1ccc(OC)cc1)C(NC)C
InChI InChI=1S/C11H15NO2/c1-8(12-2)11(13)9-4-6-10(14-3)7-5-9/h4-8,12H,1-3H3^Y Key:MQUIHBQDYYAEMH-UHFFFAOYSA-N^Y
(verify)