Metyrapone

Metyrapone

Clinical data
Trade names	Metopirone
AHFS/Drugs.com	Consumer Drug Information
Pregnancy category	C US
Routes of administration	By mouth
ATC code	V04CD01 (WHO)
Pharmacokinetic data
Elimination half-life	1.9 ± 0.7 hours
Identifiers
IUPAC name 2-methyl-1,2-di(pyridin-3-yl)propan-1-one
CAS Number	54-36-4 Y
PubChem CID	4174
IUPHAR/BPS	5224
DrugBank	DB01011 Y
ChemSpider	4030 Y
UNII	ZS9KD92H6V
KEGG	D00410 Y
ChEBI	CHEBI:44241 Y
ChEMBL	ChEMBL934 Y
CompTox Dashboard (EPA)	DTXSID1023314
ECHA InfoCard	100.000.188
Chemical and physical data
Formula	C14H14N2O
Molar mass	226.279 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C(c1cccnc1)C(c2cccnc2)(C)C
InChI InChI=1S/C14H14N2O/c1-14(2,12-6-4-8-16-10-12)13(17)11-5-3-7-15-9-11/h3-10H,1-2H3 Y Key:FJLBFSROUSIWMA-UHFFFAOYSA-N Y
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Metyrapone, sold under the brand name Metopirone, is a medication which is used in the diagnosis of adrenal insufficiency and occasionally in the treatment of Cushing's syndrome (hypercortisolism). It is part of the steroidogenesis inhibitor class of drugs.