![]() | |
![]() | |
Clinical data | |
---|---|
Trade names | Desenex, Monistat, Oravig, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a601203 |
Routes of administration | Topical, vaginal, sublabial |
ATC code | |
Legal status | |
Legal status |
|
Pharmacokinetic data | |
Bioavailability | <1% after application to the skin |
Protein binding | 88.2% |
Metabolism | CYP3A4 |
Elimination half-life | 20–25 hrs |
Excretion | Mainly feces |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
IUPHAR/BPS | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.041.188 |
Chemical and physical data | |
Formula | C18H14Cl4N2O |
Molar mass | 416.12 g·mol−1 |
3D model (JSmol) | |
Chirality | Racemic mixture |
| |
| |
(verify) |
Miconazole, sold under the brand name Monistat among others, is an antifungal medication used to treat ring worm, pityriasis versicolor, and yeast infections of the skin or vagina.[2] It is used for ring worm of the body, groin (jock itch), and feet (athlete's foot).[2] It is applied to the skin or vagina as a cream or ointment.[2][3]
Common side effects include itchiness or irritation of the area in which it was applied.[2] Use in pregnancy is believed to be safe for the baby.[4] Miconazole is in the imidazole family of medications.[2] It works by decreasing the ability of fungi to make ergosterol, an important part of their cell membrane.[2]
Miconazole was patented in 1968 and approved for medical use in 1971.[5] It is on the World Health Organization's List of Essential Medicines.[6]
© MMXXIII Rich X Search. We shall prevail. All rights reserved. Rich X Search