Mokola lyssavirus

Mokola lyssavirus
Virus classification
(unranked):	Virus
Realm:	Riboviria
Kingdom:	Orthornavirae
Phylum:	Negarnaviricota
Class:	Monjiviricetes
Order:	Mononegavirales
Family:	Rhabdoviridae
Genus:	Lyssavirus
Species:	Mokola lyssavirus
Synonyms
	Mokola virus

Mokola lyssavirus, commonly called Mokola virus (MOKV), is an RNA virus related to rabies virus that has been sporadically isolated from mammals across sub-Saharan Africa. The majority of isolates have come from domestic cats exhibiting symptoms characteristically associated to rabies virus infection.^[1]

As of 2021, there have been two confirmed cases of Mokola virus infection in humans, of which one was fatal.^[2]^[3] The rabies vaccine does not confer cross-protective immunity to Mokola virus, and no other known treatment for MOKV exists.

^ von Teichman BF, de Koker WC, Bosch SJ, Bishop GC, Meredith CD, Bingham J (December 1998). "Mokola virus infection: description of recent South African cases and a review of the virus epidemiology: case report". Journal of the South African Veterinary Association. 69 (4): 169–171. doi:10.4102/jsava.v69i4.847. PMID 10192092.
^ Familusi, J. B.; Moore, D. L. (January 1972). "Isolation of a Rabies Related Virus from the Cerebrospinal Fluid of a Child with 'Aseptic Meningitis'". African Journal of Medical Sciences. 3 (1): 93–96. PMID 5061272.
^ Familusi, J. B.; Osunkoya, B. O.; Moore, D. L.; Kemp, G. E.; Fabiyi, A. (November 1972). "A Fatal Human Infection with Mokola Virus". American Journal of Tropical Medicine and Hygiene. 21 (6): 959–963. doi:10.4269/ajtmh.1972.21.959. PMID 4635777.

[Von_Teichman12-1] von Teichman BF, de Koker WC, Bosch SJ, Bishop GC, Meredith CD, Bingham J (December 1998). "Mokola virus infection: description of recent South African cases and a review of the virus epidemiology: case report". Journal of the South African Veterinary Association. 69 (4): 169–171. doi:10.4102/jsava.v69i4.847. PMID 10192092.

[Familusi72-2] Familusi, J. B.; Moore, D. L. (January 1972). "Isolation of a Rabies Related Virus from the Cerebrospinal Fluid of a Child with 'Aseptic Meningitis'". African Journal of Medical Sciences. 3 (1): 93–96. PMID 5061272.

[Osunkoya72-3] Familusi, J. B.; Osunkoya, B. O.; Moore, D. L.; Kemp, G. E.; Fabiyi, A. (November 1972). "A Fatal Human Infection with Mokola Virus". American Journal of Tropical Medicine and Hygiene. 21 (6): 959–963. doi:10.4269/ajtmh.1972.21.959. PMID 4635777.

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