Monocarboxylate transporter 1

SLC16A1
Identifiers
Aliases	SLC16A1, HHF7, MCT, MCT1, MCT1D, solute carrier family 16 member 1
External IDs	OMIM: 600682; MGI: 106013; HomoloGene: 20662; GeneCards: SLC16A1; OMA:SLC16A1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	112,957,593 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	104,565,778 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; ventricular zone; ; smooth muscle tissue; ; left ventricle; ; endometrium; ; rectum; ; placenta; ; duodenum; ; skeletal muscle tissue; ; right auricle of heart;
	Top expressed in
	retinal pigment epithelium; ; optic nerve; ; primitive streak; ; left colon; ; atrioventricular valve; ; fetal liver hematopoietic progenitor cell; ; atrium; ; right ventricle; ; mucous cell of stomach; ; intercostal muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; monocarboxylic acid transmembrane transporter activity; mevalonate transmembrane transporter activity; organic cyclic compound binding; symporter activity; lactate transmembrane transporter activity;
Cellular component	integral component of membrane; centrosome; membrane; plasma membrane; integral component of plasma membrane; mitochondrion; extracellular exosome; cell junction; intracellular membrane-bounded organelle; synapse;
Biological process	monocarboxylic acid transport; glucose homeostasis; regulation of insulin secretion; lipid metabolism; behavioral response to nutrient; cellular response to organic cyclic compound; lactate transmembrane transport; pyruvate metabolic process; response to food; mevalonate transport; leukocyte migration; transmembrane transport; plasma membrane lactate transport; centrosome cycle; transport;
	Sources:Amigo / QuickGO
Orthologs
	6566
	20501
	ENSG00000155380; ENSG00000281917
	ENSMUSG00000032902
	P53985; Q5T8R3
	P53986
	NM_001166496; NM_003051
	NM_009196
	NP_001159968; NP_003042
	NP_033222
	Wikidata
View/Edit Human	View/Edit Mouse

Monocarboxylate transporter 1 is a ubiquitous protein that in humans is encoded by the SLC16A1 gene (also known as MCT1).^[5]^[6]^[7] It is a proton coupled monocarboxylate transporter.

^ ^a ^b ^c ENSG00000281917 GRCh38: Ensembl release 89: ENSG00000155380, ENSG00000281917 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000032902 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Cite error: The named reference pmid8124722 was invoked but never defined (see the help page).
^ Cite error: The named reference pmid7835905 was invoked but never defined (see the help page).
^ Cite error: The named reference entrez was invoked but never defined (see the help page).

[refGRCh38Ensembl-1] ENSG00000281917 GRCh38: Ensembl release 89: ENSG00000155380, ENSG00000281917 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000032902 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8124722-5] Cite error: The named reference pmid8124722 was invoked but never defined (see the help page).

[pmid7835905-6] Cite error: The named reference pmid7835905 was invoked but never defined (see the help page).

[entrez-7] Cite error: The named reference entrez was invoked but never defined (see the help page).

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