Back مناهضة مستقبل نمدا Arabic آنتاگونیست NMDA Persian Antagonisti del recettore NMDA Italian Antagonista do receptor NMDA Portuguese Антагонисты NMDA-рецептора Russian Antagonist NMDA receptora Serbo-Croatian Antagonist NMDA receptora Serbian Антагоністи NMDA-рецептора Ukrainian NMDA受体拮抗剂 Chinese
NMDA receptor antagonists are a class of drugs that work to antagonize, or inhibit the action of, the N-Methyl-D-aspartate receptor (NMDAR). They are commonly used as anesthetics for humans and non-human animals; the state of anesthesia they induce is referred to as dissociative anesthesia.
Several synthetic opioids function additionally as NMDAR-antagonists, such as pethidine, levorphanol, methadone, dextropropoxyphene, tramadol, and ketobemidone.
Some NMDA receptor antagonists, such as ketamine, dextromethorphan (DXM), phencyclidine (PCP), methoxetamine (MXE), and nitrous oxide (N2O), are sometimes used as recreational drugs, for their dissociative, hallucinogenic, and euphoriant properties. When used recreationally, they are classified as dissociative drugs.
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